Evidence map›Paper›PMID 36091751›Full record

ArticleFrontiers in pharmacology2022

KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring.

Gilbert Aaron Lee, Hong-Wei Zhao, Yu-Wei Chang, Chia-Jung Lee, Yu-Chen S H Yang, Ying-Chieh Wu, Wan-Li Lin, Yun-Ru Liu, De-Shan Ning, Sung-Hui Tseng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Gilbert Aaron LeeDepartment of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan.
Hong-Wei ZhaoInfinitus (China) Company Ltd, Guangzhou, Guangdong, China.
Yu-Wei ChangDepartment of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan.
Chia-Jung LeePhD Program for Clinical Drug Discovery of Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.
Yu-Chen S H YangJoint Biobank, Office of Human Research, Taipei Medical University, Taipei, Taiwan.
Ying-Chieh WuDepartment of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan.
Wan-Li LinDepartment of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan.
Yun-Ru LiuJoint Biobank, Office of Human Research, Taipei Medical University, Taipei, Taiwan.
De-Shan NingInfinitus (China) Company Ltd, Guangzhou, Guangdong, China.
Sung-Hui TsengDepartment of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Taipei Medical University Hospital · TWTaipei Medical University · TWInfinitus (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mushrooms and Chinese traditional herbs have bioactive nutraceuticals with multiple therapeutic functions, including antioxidant and antibacterial activities and microbiome modulation properties. Mushroom-derived bioactive compounds are used in medicines for the treatment of neurological disorders with abnormal brain

Indexed as

maternal immune activationmicrobiotamushroommyelinationoxidative stressspleen-tonifying formula

Identifiers

PMID36091751
PMCPMC9453593
OpenAlexW4293091611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.