Evidence map›Paper›PMID 36091641›Full record

ArticleBiochip journal2022

Micro-injection Molded Droplet Generation System for Digital PCR Application.

Daae Jo, So Young Kim, Hyeon Woo Kang, Sung Han Pyo, Nam Kyu Jeong, Nam Ho Bae, Seok Jae Lee, Yong Tae Kim, Kyoung G Lee

Abstract read
In one paragraph

Article in Biochip journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daae JoNational Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
So Young KimBio R&D Lab, BioTNS Co.Ltd, 19-12 Daehak-ro 76 beonan-gil, Daejeon, 34141 Republic of Korea.
Hyeon Woo KangBio R&D Lab, BioTNS Co.Ltd, 19-12 Daehak-ro 76 beonan-gil, Daejeon, 34141 Republic of Korea.
Sung Han PyoNational Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Nam Kyu JeongNational Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Nam Ho BaeNational Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Seok Jae LeeNational Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Yong Tae KimDepartment of Chemical Engineering and Biotechnology, Tech University of Korea, 237 Sangidaehak-ro, Siheung-si, Gyeonggi-do 15073 Republic of Korea.
Kyoung G LeeNational Nanofab Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sensitive, effective, and quantitative analysis of infectious pathogens is an important task for the prevention of human health threats. Herein, we present an advanced approach to producing gene-encapsulated microdroplets for quantitative analysis using a micropatterned metal mold and injection molding technique with an automatically operated system. An injection molded microdroplet generation device was successfully fabricated with a minimum channel width of 30 μm and optimized to produce 100 μm diameter droplets. The optimized microchannel design and flow rate also enable the production of stable numbers of microdroplets (~ 16,000 droplets). To verify the applicability of our device and system to droplet-based digital PCR analysis,

Indexed as

Digital nucleic acid assayDigital PCRMetal moldMicrodropletMicropattern

Identifiers

PMID36091641
PMCPMC9446600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.