Evidence map›Paper›PMID 36091465›Full record

ArticleFrontiers in bioengineering and biotechnology2022

3D-printed collagen/silk fibroin/secretome derived from bFGF-pretreated HUCMSCs scaffolds enhanced therapeutic ability in canines traumatic brain injury model.

Xiaoyin Liu, Guijun Zhang, Pan Wei, Lifang Hao, Lin Zhong, Kunhon Zhong, Chang Liu, Peng Liu, Qingbo Feng, Shan Wang and 3 more

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  12. The paradigm of stem cell secretome in tissue repair and regeneration: Present and future perspectives.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaoyin LiuDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Guijun ZhangDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Pan WeiDepartment of Neurosurgery, The First People's Hospital of Long Quan yi District, Chengdu, China.
Lifang HaoDepartment of Radiology, Liao Cheng The Third People's Hospital, Liaocheng, China.
Lin ZhongThe First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Kunhon ZhongState Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Chang LiuDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Peng LiuDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Qingbo FengDepartment of Liver Surgery and Liver Transplantation, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Shan WangDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Jianyong ZhangDepartment of General Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Rui TianDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
Liangxue ZhouDepartment of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regeneration of brain tissue poses a great challenge because of the limited self-regenerative capabilities of neurons after traumatic brain injury (TBI). For this purpose, 3D-printed collagen/silk fibroin/secretome derived from human umbilical cord blood mesenchymal stem cells (HUCMSCs) pretreated with bFGF scaffolds (3D-CS-bFGF-ST) at a low temperature were prepared in this study. From an

Indexed as

bFGFcollagenhuman umbilical cord blood mesenchymal stem cellssecretomesilk fibrointraumatic brain injury

Identifiers

PMID36091465
PMCPMC9449499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.