ArticleFrontiers in physiology2022
Iron supplementation inhibits hypoxia-induced mitochondrial damage and protects zebrafish liver cells from death.
Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 10 citations in OpenAlex.
- Ferritin Associates with Interspecific Variation in Iron Accumulation among Five Economically Important Bivalves: Sequence, Expression, and Functional Analyses.Biological trace element research · 2026Article
- Article
- Lysosome-Iron-Mitochondria Axis in Osteoclasts: Iron as a Central Player.Research (Washington, D.C.) · 2025Review
- Long-term iron supplementation combined with vitamin B6 enhances maximal oxygen uptake and promotes skeletal muscle-specific mitochondrial biogenesis in rats.Frontiers in nutrition · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
Acute hypoxia in water has always been a thorny problem in aquaculture. Oxygen and iron play important roles and are interdependent in fish. Iron is essential for oxygen transport and its concentration tightly controlled to maintain the cellular redox homeostasis. However, it is still unclear the role and mechanism of iron in hypoxic stress of fish. In this study, we investigated the role of iron in hypoxic responses of two zebrafish-derived cell lines. We found hypoxia exposed zebrafish liver cells (ZFL) demonstrated reduced expression of Ferritin and the gene
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