Evidence map›Paper›PMID 36091351›Full record

ArticleAfrican journal of laboratory medicine2022

Hepatitis B virus infection and HBeAg positivity among pregnant women in South West Uganda.

Naome Mugabiirwe, Rogers Kalyetsi, Richard Ayella, James Obote, Frank Ssedyabane

Open access · diamondAbstract read
In one paragraph

Article in African journal of laboratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Naome MugabiirweDepartment of Medical Laboratory, Kyazanga Health Centre IV, Lwengo, Uganda.ORCID https://orcid.org/0000-0002-5148-6501
Rogers KalyetsiDepartment of Medical Laboratory Science, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.ORCID https://orcid.org/0000-0002-4232-7875
Richard AyellaDepartment of Medical Laboratory, Kyazanga Health Centre IV, Lwengo, Uganda.ORCID https://orcid.org/0000-0002-4592-830X
James OboteDepartment of Medical Laboratory, Kyazanga Health Centre IV, Lwengo, Uganda.ORCID https://orcid.org/0000-0003-1693-736X
Frank SsedyabaneDepartment of Medical Laboratory Science, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.ORCID https://orcid.org/0000-0002-4666-1379
World Health Organization - Uganda · UGMbarara University of Science and Technology · UG

Funding

Multi-morbidity in Uganda Research Capacity Initiative (MURCI) at Mbarara University of Science and TechnologyD43TW011632 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI BAJUNIRWE, FRANCIS · 2020 to 2024
$1.2M
FIC NIH HHS D43 TW011632
6 · The paper itself

Abstract

Background: Hepatitis B virus is a public health burden in Uganda, yet little is known about its epidemiology in pregnancy. Objective: This study aimed at determining the prevalence and associated risk factors of hepatitis B virus infection among pregnant women attending antenatal care at the Kyazanga Health Centre IV in Lwengo District, Uganda. Methods: This cross-sectional study was conducted from April 2021 to June 2021 and analysed qualitative data that were collected using a structured in-person questionnaire. Aseptically collected blood specimens were screened for hepatitis B virus infection using an immunochromatographic rapid diagnostic test kit. Participants who were positive for the hepatitis B surface antigen (HBsAg) were further screened for hepatitis B envelope antigen (HBeAg) using commercial rapid diagnostic test kits. Results: Out of 384 pregnant women studied, eight tested positive for HBsAg. This gave a prevalence of 2.1% (95% confidence interval: 1.0% - 4.1%); 5/8 (62.5%) were positive for HBeAg. None of the variables studied were significantly associated with HBsAg positivity among pregnant women. Conclusion: Hepatitis B viral infection is still a public health challenge in pregnant women with possible risk for vertical transmission to their babies in the study area. We recommend routine screening for hepatitis B virus in pregnancy in addition to strengthening current strategies aimed at controlling and preventing hepatitis B infection spread and transmission.

Indexed as

hepatitis Bpregnant womenprevalencerisk factorsUganda

Identifiers

PMID36091351
PMCPMC9453108
OpenAlexW4292099879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.