Evidence map›Paper›PMID 36091348›Full record

ArticleAfrican journal of laboratory medicine2022

Effect of sputum quality and role of Xpert

Waganeh Sinshaw, Abebaw Kebede, Adane Bitew, Mengistu Tadesse, Zemedu Mehamed, Ayinalem Alemu, Bazezew Yenew, Misikir Amare, Biniyam Dagne, Getu Diriba and 6 more

Open access · diamondAbstract read
In one paragraph

Article in African journal of laboratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Closing gaps through innovation in the tuberculosis pathology value chain.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The impact of sputum quality on Xpert positivity in active case-finding for TB.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Waganeh SinshawTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-6212-4055
Abebaw KebedeTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-6154-7275
Adane BitewDepartment of Medical Laboratory Science, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-5518-1342
Mengistu TadesseTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-9390-0355
Zemedu MehamedTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-4404-8968
Ayinalem AlemuTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-5307-8774
Bazezew YenewTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-8505-7000
Misikir AmareTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-6840-4229
Biniyam DagneTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-5930-2690
Getu DiribaTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-0166-682X
Ephrem TesfayeTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-8859-1906
Dinka F GamtesaTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-6261-541X
Yeshiwork AbebawTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-6039-3430
Helina Molallign MollalignTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-1918-0668
Getachew SeidTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0002-8708-386X
Muluwork GetahunTuberculosis Research Unit/National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0003-3407-983X
Ethiopian Public Health Institute · ETAddis Ababa University · ET

Funding

Ethiopia-Emory TB Research Training ProgramD43TW009127 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Kidist Bobosha · 2013 to 2026
$3.4M
FIC NIH HHS D43 TW009127
6 · The paper itself

Abstract

Background: There is limited information on the performance of the Xpert Objective: This study aimed to determine the performance of the Xpert Methods: A cross-sectional study was conducted from August 2017 to January 2018 across 16 health facilities in Addis Ababa, Ethiopia. Two spot sputum samples were collected from 418 presumptive SNPT patients, tested with Xpert® MTB/RIF, then compared to tuberculosis culture. Additionally, culture isolates were tested for RR by BACTEC MGIT™ 960 drug susceptibility testing (DST) and MTBDRplus version 2. Results: The Xpert Conclusion: The performance of the Xpert

Indexed as

diagnostic performancesmear-negative pulmonary tuberculosissputum qualitytuberculosis cultureXpert® MTB/RIF test

Identifiers

PMID36091348
PMCPMC9453192
OpenAlexW4294281310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.