Evidence map›Paper›PMID 36091251›Full record

ArticleFrontiers in nutrition2022

Feeding foliar nano-selenium biofortified panax notoginseng could reduce the occurrence of glycolipid metabolism disorder in mice caused by high-fat diets.

Qinyong Dong, Sen Yan, Dong Li, Chunran Zhou, Sinuo Tian, Yu Wang, Peijuan Miao, Wentao Zhu, Shusheng Zhu, Canping Pan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. The Impact ofMicroorganisms · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qinyong DongDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Sen YanDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Dong LiDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Chunran ZhouDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Sinuo TianDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Yu WangDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Peijuan MiaoDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Wentao ZhuDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
Shusheng ZhuState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, College of Plant Protection, National Engineering Research Center for Applied Technology of Agricultural Biodiversity, Yunnan Agricultural University, Kunming, China.
Canping PanDepartment of Applied Chemistry, College of Science, Innovation Center of Pesticide Research, China Agricultural University, Beijing, China.
China Agricultural University · CNYunnan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nano-selenium (nano-Se) has been extensively explored as a biostimulant for improving the quality of grain crops. However, there are few reports about the effect on the medicinal components of Chinese herbal medicine cultured with nano-Se. Here, we sprayed nano-Se during the cultivation of Panax notoginseng (SePN), and measured the changes of medicinal components compared with conventional Panax notoginseng (PN). Furthermore, we identified a more pronounced effect of SePN on reducing obesity in animals compared with PN. By measuring antioxidant capacity, histopathology, gene expression related to glycolipid metabolism, and gut microbiota composition, we propose a potential mechanism for SePN to improve animal health. Compared with the control groups, foliar spraying of nano-Se increased saponins contents (Rb2, Rb3, Rc, F2, Rb2, and Rf) in the roots of Panax notoginseng, the content of Rb2 increased by 3.9 times particularly. Interestingly, animal studies indicated that taking selenium-rich Panax notoginseng (SePN) can further ameliorate liver antioxidation (SOD, MDA, and GSH) and enzyme activities involved in glycolipid metabolism (ATGL and PFK). It also relieved inflammation and regulated the expression of genes (

Indexed as

glycolipid metabolismgut microbiotahigh-fat dietnano-seleniumPanax notoginseng

Identifiers

PMID36091251
PMCPMC9450130
OpenAlexW4293213292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.