Evidence map›Paper›PMID 36091245›Full record

ArticleFrontiers in nutrition2022

Cyanidin-3-

Yanshuai Wang, Jiebiao Chen, Yue Wang, Fanghong Zheng, Meiyu Qu, Ziwei Huang, Jialang Yan, Fangping Bao, Xian Li, Chongde Sun and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
  5. Review
  6. Review
  7. Potential Surviving Effect ofAntibiotics (Basel, Switzerland) · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yanshuai WangDepartment of General Surgery, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu, China.
Jiebiao ChenLaboratory of Fruit Quality Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development, and Quality Improvement, Fruit Science Institute, Zhejiang University, Hangzhou, China.
Yue WangLaboratory of Fruit Quality Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development, and Quality Improvement, Fruit Science Institute, Zhejiang University, Hangzhou, China.
Fanghong ZhengDepartment of General Surgery, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu, China.
Meiyu QuDepartment of Pharmacology, School of Medicine, Zhejiang University, Hangzhou, China.
Ziwei HuangDepartment of General Surgery, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu, China.
Jialang YanDepartment of General Surgery, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu, China.
Fangping BaoDepartment of Anesthesiology, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu, China.
Xian LiLaboratory of Fruit Quality Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development, and Quality Improvement, Fruit Science Institute, Zhejiang University, Hangzhou, China.
Chongde SunLaboratory of Fruit Quality Biology, The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development, and Quality Improvement, Fruit Science Institute, Zhejiang University, Hangzhou, China.
Yixiong ZhengDepartment of General Surgery, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu, China.
Zhejiang University · CNFruit Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chinese bayberry has been used to treat diarrhea in China for more than 2,000 years, but the mechanism is not clear. Due to the extensive use of antibiotics, antibiotic-associated diarrhea (AAD) is becoming more and more common in clinic, but there is no effective drug for the treatment. The present study aimed to explore the therapeutic effect of Chinese bayberry on AAD for the first time, and explained the underlying mechanism from different aspects. The BALB/c mice model was established by intragastric administration of lincomycin (3 g/kg). Successfully modeled mice were treated with purified water, dried bayberry powder suspension (100 mg/kg), C3G suspension (40 mg/kg) and montmorillonite powder suspension (40 mg/kg), respectively. The changes of body weight, diarrhea index, diarrhea status score were recorded and calculated regularly. 16S rRNA gene sequencing, intestinal immunofluorescence and inflammatory factor detection were further performed. The treatment with dried bayberry powder suspension and C3G suspension could rapidly reduce the diarrhea score and diarrhea index, increase food intake and restore body weight gain. The gut microbiota richness and diversity were significantly increased after dried bayberry powder suspension and C3G suspension treatments, typically decreased bacterial genera

Indexed as

antibiotic-associated diarrheaChinese bayberrycyanidin-3-O-glucosidegut microbiota homeostasisintestinal tight junction protein

Identifiers

PMID36091245
PMCPMC9449314
OpenAlexW4293214256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.