Evidence map›Paper›PMID 36091053›Full record

ReviewFrontiers in immunology2022

COVID-19 pandemic: A multidisciplinary perspective on the pathogenesis of a novel coronavirus from infection, immunity and pathological responses.

Jia Yi, Jiameng Miao, Qingwei Zuo, Felix Owusu, Qiutong Dong, Peizhe Lin, Qilong Wang, Rui Gao, Xianbin Kong, Long Yang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jia YiCollege of Traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Jiameng MiaoCollege of Traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Qingwei ZuoResearch Center for Infectious Diseases, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Felix OwusuInstitute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Qiutong DongCollege of Traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Peizhe LinCollege of Traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Qilong WangInstitute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Rui GaoInstitute of Clinical Pharmacology of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xianbin KongCollege of Traditional Chinese medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Long YangResearch Center for Infectious Diseases, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Tianjin University of Traditional Chinese Medicine · CNXiyuan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), has spread to more than 200 countries and regions, having a huge impact on human health, hygiene, and economic activities. The epidemiological and clinical phenotypes of COVID-19 have increased since the onset of the epidemic era, and studies into its pathogenic mechanisms have played an essential role in clinical treatment, drug development, and prognosis prevention. This paper reviews the research progress on the pathogenesis of the novel coronavirus (SARS-CoV-2), focusing on the pathogenic characteristics, loci of action, and pathogenic mechanisms leading to immune response malfunction of SARS-CoV-2, as well as summarizing the pathological damage and pathological manifestations it causes. This will update researchers on the latest SARS-CoV-2 research and provide directions for future therapeutic drug development.

Indexed as

COVID-19PandemicsHumansSARS-CoV-2COVID-19immune pathogenesispathogenic mechanismSARS-CoV-2virus infected

Identifiers

PMID36091053
PMCPMC9459044
OpenAlexW4293206972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.