Evidence map›Paper›PMID 36091040›Full record

ArticleFrontiers in immunology2022

The deficiency in Th2-like Tfh cells affects the maturation and quality of HIV-specific B cell response in viremic infection.

Alessandra Noto, Madeleine Suffiotti, Victor Joo, Antonio Mancarella, Francesco A Procopio, Guy Cavet, Yvonne Leung, Jean-Marc Corpataux, Matthias Cavassini, Agostino Riva and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. HIV reservoirs in lymphomagenesis: hidden driver in the era of viral suppression?Microbiology and molecular biology reviews : MMBR · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Alessandra NotoService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Madeleine SuffiottiService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Victor JooService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Antonio MancarellaService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Francesco A ProcopioService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Guy CavetAtreca, Redwood City, CA, United States.
Yvonne LeungAtreca, Redwood City, CA, United States.
Jean-Marc CorpatauxService of Vascular Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Matthias CavassiniService of Infectious Diseases, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Agostino RivaDivision of Infectious Diseases, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Leonidas StamatatosDepartment of Global Health, Seattle University of Washington, Seattle, WA, United States.
Raphael GottardoVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.
Adrian B McDermottVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Richard A KoupVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Craig FenwickService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Matthieu PerreauService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Giuseppe PantaleoService Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
University of Lausanne · CHFred Hutch Cancer Center · USNational Institute of Allergy and Infectious Diseases · USNational Institutes of Health · USSwiss Vaccine Research Institute · CHUniversity of Milan · ITUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal T follicular helper (Tfh) cells function is important to promote the development of germinal centers and maturation of high affinity antigen-specific B cells. We have found that the expression of CXCR3 defines distinct Tfh subsets: CXCR3

Indexed as

HIV InfectionsT Follicular Helper CellsCytokinesGerminal CenterHumansInterleukin-4ViremiaCytokinesInterleukin-4follicular T helper cellsgerminal center B cells (GC B cells)HIV-1 infectionlymph nodesT helper cell

Identifiers

PMID36091040
PMCPMC9450063
OpenAlexW4293173531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.