Evidence map›Paper›PMID 36090792›Full record

ArticleFrontiers in cellular neuroscience2022

A requirement for astrocyte IP

John B Butcher, Robert E Sims, Neville M Ngum, Amjad H Bazzari, Stuart I Jenkins, Marianne King, Eric J Hill, David A Nagel, Kevin Fox, H Rheinallt Parri and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Neuron-Glial Interactions: Implications for Plasticity, Behavior, and Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

John B ButcherSchool of Life Sciences, Keele University, Keele, United Kingdom.
Robert E SimsCollege of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Neville M NgumCollege of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Amjad H BazzariCollege of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Stuart I JenkinsNeural Tissue Engineering Group, Institute for Science and Technology in Medicine (ISTM), Keele University, Keele, United Kingdom.
Marianne KingCollege of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Eric J HillCollege of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
David A NagelAston Medical School, Aston Medical Research Institute, Aston University, Birmingham, United Kingdom.
Kevin FoxSchool of Biosciences, Cardiff University, Cardiff, United Kingdom.
H Rheinallt ParriCollege of Health and Life Sciences, Aston University, Birmingham, United Kingdom.
Stanislaw GlazewskiSchool of Life Sciences, Keele University, Keele, United Kingdom.
Aston University · GBKeele University · GBCardiff University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes to sensory experience result in plasticity of synapses in the cortex. This experience-dependent plasticity (EDP) is a fundamental property of the brain. Yet, while much is known about neuronal roles in EDP, very little is known about the role of astrocytes. To address this issue, we used the well-described mouse whiskers-to-barrel cortex system, which expresses a number of forms of EDP. We found that all-whisker deprivation induced characteristic experience-dependent Hebbian depression (EDHD) followed by homeostatic upregulation in L2/3 barrel cortex of wild type mice. However, these changes were not seen in mutant animals (IP

Indexed as

BCMHebbian plasticityhomeostatic plasticityLTD (long term depression)LTP (long term potentiation)somatosensorysynaptic plasticity

Identifiers

PMID36090792
PMCPMC9452848
OpenAlexW4293089852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.