Evidence map›Paper›PMID 36090775›Full record

ReviewTransplant international : official journal of the European Society for Organ Transplantation2022

Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells.

Cataldo Pignatelli, Francesco Campo, Alessia Neroni, Lorenzo Piemonti, Antonio Citro

Open access · goldAbstract readReview
In one paragraph

Review in Transplant international : official journal of the European Society for Organ Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. ESOT Roadmap for Advanced Therapy Medicinal Products in Transplantation: Navigating Regulatory Challenges to Enhance Access and Care.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  9. Review
  10. Review
  11. Preferred Islet Delivery Device Characteristics and Implantation Strategies of Patients With Type 1 Diabetes.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Cataldo PignatelliSan Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesco CampoSan Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Alessia NeroniSan Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Lorenzo PiemontiSan Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Antonio CitroSan Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITVita-Salute San Raffaele University · ITIstituto di Ricovero e Cura a Carattere Scientifico San Raffaele

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrahepatic islet transplantation is a promising β-cell replacement strategy for the treatment of type 1 diabetes. Instant blood-mediated inflammatory reactions, acute inflammatory storm, and graft revascularization delay limit islet engraftment in the peri-transplant phase, hampering the success rate of the procedure. Growing evidence has demonstrated that islet engraftment efficiency may take advantage of several bioengineering approaches aimed to recreate both vascular and endocrine compartments either

Indexed as

InsulinsIslets of LangerhansIslets of Langerhans TransplantationBioengineeringExtracellular MatrixHumansInsulins3D- bioprintingalternative endocrine sourcesbeta cell replacementbioengineeringbiomaterialsextracellular matrixtype 1 diabetesvascularized endocrine pancreas

Identifiers

PMID36090775
PMCPMC9452644
OpenAlexW4293218858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.