ArticleHealth science reports2022
Evaluation of serum lipid profiles, uric acid, and high sensitivity C-reactive protein levels between pregnancy-induced hypertension and normotensive pregnant women attending Ambo University Referral Hospital, Ambo, Ethiopia, 2020: A case-control study.
Article in Health science reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 12 citations in OpenAlex.
- Late-pregnancy air pollution exposure and neonatal anthropometry with and without gestational hypertension.iScience · 2026Article
- Association Between Total Cholesterol-to-High-Density Lipoprotein Ratio and Gestational Hypertension: A Case-Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Article
- Expression of long non-coding RNA GAS5 by first trimester screening predicts the occurrence of gestational hypertension and pre-eclampsia.Journal of assisted reproduction and genetics · 2024Article
- The Impact of Serum Uric Acid Levels on Hypertensive Disorders of Pregnancy in Advanced Maternal Age Women: A Retrospective Study from a Single Center in China.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Role of coagulation indices in assessinghypertensive disorders in pregnancy and predicting delivery outcomes.American journal of translational research · 2024Article
- Establishment of trimester-specific reference intervals of renal function tests and their predictive values in pregnant complications and perinatal outcomes: A population-based cohort study.Practical laboratory medicine · 2023Article
- Article
- Evaluation of serum lipid profiles, uric acid, and high sensitivity C-reactive protein levels between pregnancy-induced hypertension and normotensive pregnant women attending Ambo University Referral Hospital, Ambo, Ethiopia, 2020: A case-control study.Health science reports · 2022Article
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Authors and funding
4 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Pregnancy-induced hypertension is one of the top three ranked diseases during pregnancy that cause maternal, fetal, and neonatal morbidity and mortality worldwide. To provide adequate information to clinicians and researchers who are striving for potential interventions, biochemical profiling of such patients is required. Methods: A hospital-based case-control study design was conducted from August 2020 to May 2021 to evaluate serum lipid profile, uric acid, and high sensitivity C-reactive protein (hs-CRP) among women with pregnancy-induced hypertension compared to normotensive pregnant women. Data were entered and analyzed using SPSS version 25. Independent Results: The result of this study showed that while the levels (mean ± SD) of serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), TC/high-density lipoprotein-cholesterol (HDL-C), TG/HDL-C, LDL-C/HDL-C were significantly elevated, HDL-C was decreased among women with pregnancy-induced hypertension than normotensive pregnant women ( Conclusion: This study indicated that pregnancy-induced hypertension women have lipid abnormalities, increased systemic inflammatory markers, and hyperuricemia compared to normotensive pregnant women. Thus, women with PIH showing high dyslipidemia, hyperuricemia, and inflammation are likely to develop hypertension. Therefore, evaluation of these potential biomarkers during early antenatal care services may help seek interventions in PIH.
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