ReviewTrends in food science & technology2022
Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health.
Review in Trends in food science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Multi-omics profiling of high-carotenoid hybrid potato lines reveals coordinated metabolic reprogramming and associates with distinct tuber microbiota.NPJ science of food · 2026Article
- Comprehensive nutritional analysis of 95 oat cultivars reveals large variability in nutritional profile: protein, starch, fat, β-glucan and fibre.NPJ science of food · 2026Article
- Germination-Driven Modulation of Phenolic Compounds in Sorghum: Bioactivity and Gene Expression.Foods (Basel, Switzerland) · 2026Review
- The Germination Paradox in Sorghum: A Review.Foods (Basel, Switzerland) · 2026Review
- Integrated metabolomic and transcriptomic analysis of anthocyanin accumulation mechanisms in maize kernels of different colors.Frontiers in genetics · 2026Article
- Polyphenol metabolites in fermented foods: biotransformation, bioavailability, and functional roles.Frontiers in nutrition · 2026Review
- Mechanisms, Functions, Research Methods and Applications of Starch-Polyphenol Complexes in the Synergistic Regulation of Physiological Parameters.Foods (Basel, Switzerland) · 2025Review
- Towards Improved Bioavailability of Cereal Inositol Phosphates,Molecules (Basel, Switzerland) · 2025Review
- Protective Effects of Cereal-Based Fermented Beverages Against 5-Fluorouracil-Induced Intestinal Damage in Mice.Nutrients · 2024Article
- Overview of the Metabolite Composition and Antioxidant Capacity of Seven Major and Minor Cereal Crops and Their Milling Fractions.Journal of agricultural and food chemistry · 2024Article
- Metabolomic analysis reveals the positive effects of Rhizopus oryzae fermentation on the nutritional and functional constituents of adlay millet seeds.Scientific reports · 2024Article
- Dynamic metabolite QTL analyses provide novel biochemical insights into kernel development and nutritional quality improvement in common wheat.Plant communications · 2024Article
- Depicting the genetic and metabolic panorama of chemical diversity in the tea plant.Plant biotechnology journal · 2024Article
- Maize hydroxycinnamic acids: unveiling their role in stress resilience and human health.Frontiers in nutrition · 2024Review
- Metabolomics and machine learning technique revealed that germination enhances the multi-nutritional properties of pigmented rice.Communications biology · 2023Article
- Relationship between Dietary Polyphenols and Gut Microbiota: New Clues to Improve Cognitive Disorders, Mood Disorders and Circadian Rhythms.Foods (Basel, Switzerland) · 2023Review
- Agro-morphological and biochemical responses of quinoa (Frontiers in plant science · 2023Article
- Anthocyanins in metabolites of purple corn.Frontiers in plant science · 2023Review
- Natural variation inFrontiers in plant science · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Whole grain cereals are a good source of nutrients. Several cutting-edge metabolomic platforms have been deployed to identify various phenolic compounds and enhance cereal bioactive bioavailability. A diet rich in cereal phenolics may modify the microbial composition, support gut homeostasis, and increase gut health, thereby lowering the risk of non-communicable illness. Scope and approach: In this work, we reviewed current metabolomic breakthroughs in cereal phenolic profiling and their effects on human health via gut microbiota modulation. We argue that the information presented in this paper will assist in the development of nutritionally superior cereal breeds and functional foods. Key findings and conclusion: Most cereal grains contain ferulic acid derivatives, caffeoyl glycerides, and feruloyl and coumaroyl esters. While there has been significant progress in discovering novel phenolic compounds in cereals, quantifying these molecules, and translating their therapeutic effects from animal model systems to humans remains a challenge. To this end, metabolomics, and other high-throughput-omics-based platforms must be integrated to further examine the structure and functionality of phenolic metabolites to breed nutritionally rich cereals as well as map their influence on human health benefits. Rare alleles must be introduced to improve bioactive content in cereal grains while maintaining yield. Following that, these exceptional varieties must be effectively processed to maximize phenolic bioavailability.
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Registered trials
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