Evidence map›Paper›PMID 36090413›Full record

ArticleRSC advances2022

β-cyclodextrin dendritic derivatives as permeation mediators to enhance the

Luis José López-Méndez, Francisca Palomares-Alonso, Iliana González-Hernández, Helgi Jung-Cook, Neyra Citlali Cabrera-Quiñones, Patricia Guadarrama

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. In Vitro Evaluation of Esters of Quinoxaline-1,4-di-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Luis José López-MéndezUniversidad Autónoma Metropolitana Unidad Xochimilco Calzada del Hueso 1100, Villa Quietud, Coyoacán 04960 CDMX Mexico.ORCID https://orcid.org/0000-0002-1567-1486
Francisca Palomares-AlonsoLaboratorio de Neuropsicofarmacología, Instituto Nacional de Neurología y Neurocirugía 14269 CDMX Mexico.
Iliana González-HernándezLaboratorio de Neuropsicofarmacología, Instituto Nacional de Neurología y Neurocirugía 14269 CDMX Mexico.
Helgi Jung-CookLaboratorio de Neuropsicofarmacología, Instituto Nacional de Neurología y Neurocirugía 14269 CDMX Mexico.
Neyra Citlali Cabrera-QuiñonesInstituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México 04510 CDMX Mexico patriciagua@materiales.unam.mx.
Patricia GuadarramaInstituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México 04510 CDMX Mexico patriciagua@materiales.unam.mx.
Instituto Nacional de Neurología y Neurocirugía · MXUniversidad Nacional Autónoma de México · MXUniversidad Autónoma Metropolitana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The improvement of permeation of drugs across parasites' membranes to promote their diffusion component represents a challenge to achieve better therapeutic effects, including the avoidance of drug resistance. In the context of medicinal chemistry, suitable structural modifications can be made, either on a drug or a nanocarrier, to trigger different mechanisms that promote the influx across membranes. This study aimed to demonstrate the potential of a set of dendritic derivatives of β-cyclodextrin (m2G, h2G, and m3G) as nanocarriers, based on their physicochemical and biological behavior in terms of (i) stability, monitored by

Identifiers

PMID36090413
PMCPMC9382653
OpenAlexW4292084612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.