Evidence map›Paper›PMID 36090301›Full record

ReviewIndian journal of clinical biochemistry : IJCB2023

A comprehensive overview on Micro RNA signature in type 2 diabetes Mellitus and its complications.

Sanjukta Mishra, Jyotirmayee Bahinipati, RajLaxmi Sarangi, Soumya Ranjan Mohapatra, Swarnalata Das, Amaresh Mishra

Open access · bronzeAbstract readReview
In one paragraph

Review in Indian journal of clinical biochemistry : IJCB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Small interfering RNA: From designing to therapeutic in cancer.Journal, genetic engineering & biotechnology · 2025
    Review
  3. Article
  4. Oxidative Stress, Endothelial Dysfunction, andAntioxidants & redox signaling · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sanjukta MishraDepartment of Biochemistry, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Campus 5, 751024 Bhubaneswar, Odisha India.
Jyotirmayee BahinipatiDepartment of Biochemistry, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Campus 5, 751024 Bhubaneswar, Odisha India.ORCID 0000-0003-3901-5210
RajLaxmi SarangiDepartment of Biochemistry, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Campus 5, 751024 Bhubaneswar, Odisha India.
Soumya Ranjan MohapatraDepartment of Research & Development, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Campus 5, 751024 Bhubaneswar, Odisha India.
Swarnalata DasDepartment of Paediatrics, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha India.
Amaresh MishraDepartment of Surgery, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha India.
Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small endogenous, non-coding RNA molecules that can modulate the expression of their target genes. Since its discovery, an enormous breakthrough has been established regarding its biogenesis and pathophysiological action, which has revolutionized the field of molecular biology. In addition, recent studies have identified the existence of stable extracellular/circulating miRNAs tissues and in biological fluids like blood where they are safeguarded from endogenous ribonuclease activity. Type 2 diabetes mellitus (T2DM) has emerged as a prime health issue worldwide. Incidence has increased considerably over the past decade. There are various tests that have been employed to diagnose T2DM. But for early detection and development, the establishment of biomarkers are of paramount importance. Contemporary evidence also validates the signature of a set of this epigenetic factor miRNA in the development of various diseases, including T2DM. This article reviews the contemporary corroboration associating miRNAs and T2DM and emphasizes the potential role of miRNA as a circulatory biomarker that could alert the growing prevalence of T2DM. Also, it acknowledges the valuable compendium of information regarding biogenesis and functional role of circulating miRNA in insulin resistance which is intimately linked to T2DM. Supplementary Information: The online version contains supplementary material available at 10.1007/s12291-022-01069-1.

Indexed as

Diabetes mellitusInsulin resistancemicroRNA

Identifiers

PMID36090301
PMCPMC9441834
OpenAlexW4294600468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.