Evidence map›Paper›PMID 36090241›Full record

ArticleInternational journal of MS care

Effects of Nonconsecutive Sessions of Transcranial Direct Current Stimulation and Stationary Cycling on Walking Capacity in Individuals With Multiple Sclerosis.

Sarvenaz Rahimibarghani, Mohaddeseh Azadvari, Seyede Zahra Emami-Razavi, Mohammad Hossein Harirchian, Shahram Rahimi-Dehgolan, Hamid R Fateh

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of MS care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sarvenaz RahimibarghaniPhysical Medicine and Rehabilitation Department (SR, MA, SZE-R, SR-D, HRF), Tehran University of Medical Sciences, Tehran, Iran.
Mohaddeseh AzadvariPhysical Medicine and Rehabilitation Department (SR, MA, SZE-R, SR-D, HRF), Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-6860-0403
Seyede Zahra Emami-RazaviPhysical Medicine and Rehabilitation Department (SR, MA, SZE-R, SR-D, HRF), Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein HarirchianIranian Center of Neurological Research, Neuroscience Institute (MHH), Tehran University of Medical Sciences, Tehran, Iran.
Shahram Rahimi-DehgolanPhysical Medicine and Rehabilitation Department (SR, MA, SZE-R, SR-D, HRF), Tehran University of Medical Sciences, Tehran, Iran.
Hamid R FatehPhysical Medicine and Rehabilitation Department (SR, MA, SZE-R, SR-D, HRF), Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise has been demonstrated to be safe and well-tolerated in individuals with multiple sclerosis (MS). Physical activity has been shown to enhance the therapeutic effects of transcranial direct current stimulation (tDCS). This study aimed to determine the efficacy of intermittent tDCS combined with riding a stationary bicycle to improve walking capacity in individuals with MS.

methodsThis double-blind randomized controlled trial enrolled 50 eligible participants. Thirty-nine participants completed the study: 21 in the active group and 18 in the control group. Participants were assigned randomly to exercise on a stationary bike in conjunction with anodal tDCS or to exercise combined with a sham tDCS protocol. Walking capacity tests (2-Minute Walk Test, 5-Meter Walk Test, Timed Up and Go test), manual muscle testing, the Fatigue Severity Scale, and the Multiple Sclerosis Quality of Life-54 were used to determine outcomes.

resultsIn terms of observed changes in 2-Minute Walk Test and 5-Meter Walk Test values, the exercise + tDCS group achieved significantly higher posttreatment values than the exercise + sham tDCS group. After the intervention and 1 month later, the intervention group's mean Timed Up and Go test value decreased significantly (

conclusionsNonconsecutive sessions of anodal tDCS combined with stationary cycling may have a greater effect on the walking capacity of individuals with MS than exercise alone.

Indexed as

exercisemultiple sclerosisrehabilitationtranscranial direct current stimulationwalking capacity

Identifiers

PMID36090241
PMCPMC9461723
OpenAlexW4283326784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.