Evidence map›Paper›PMID 36090151›Full record

ArticlemicroPublication biology2022

Fission yeast Dap1 heme iron-coordinating residue Y83 is required for cytochromes P450 function.

Shan Zhao, Adam L Hughes, Peter J Espenshade

Open access · greenAbstract read
In one paragraph

Article in microPublication biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shan ZhaoJohns Hopkins University School of Medicine, USA.
Adam L HughesJohns Hopkins University School of Medicine, USA.
Peter J EspenshadeJohns Hopkins University School of Medicine, USA.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Regulation of Cellular Cholesterol HomeostasisR01HL077588 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ESPENSHADE, PETER J. · 2004 to 2022
$7.8M
NHLBI NIH HHS R01 HL077588
6 · The paper itself

Abstract

Fission yeast Dap1 is a heme binding protein required for cytochromes P450 activity. Here, we tested whether Dap1 axial coordination of heme iron is required for its role in the function of the cytochrome P450 enzymes, Erg5 and Erg11. Two different

Identifiers

PMID36090151
PMCPMC9449707
OpenAlexW4295441520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.