Evidence map›Paper›PMID 36090012›Full record

ArticlePhotoacoustics2022

Multispectral raster-scanning optoacoustic mesoscopy differentiate lesional from non-lesional atopic dermatitis skin using structural and functional imaging markers.

Xiuting Li, Mohesh Moothanchery, Cheng Yi Kwa, Wan Ling Tan, Yik Weng Yew, Steven Tien Guan Thng, U S Dinish, Amalina Binte Ebrahim Attia, Malini Olivo

Open access · goldAbstract read
In one paragraph

Article in Photoacoustics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. S1 guideline for imaging diagnostics for skin diseases.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Guideline
  2. Pooled it
  3. Review
  4. Article
  5. Photoacoustics · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Journal of biomedical optics · 2023
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiuting LiTranslational Biophotonics Laboratory, Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A⁎STAR), Singapore.
Mohesh MoothancheryTranslational Biophotonics Laboratory, Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A⁎STAR), Singapore.
Cheng Yi KwaNational Skin Centre, Singapore.
Wan Ling TanNational Skin Centre, Singapore.
Yik Weng YewNational Skin Centre, Singapore.
Steven Tien Guan ThngNational Skin Centre, Singapore.
U S DinishTranslational Biophotonics Laboratory, Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A⁎STAR), Singapore.
Amalina Binte Ebrahim AttiaTranslational Biophotonics Laboratory, Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A⁎STAR), Singapore.
Malini OlivoTranslational Biophotonics Laboratory, Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A⁎STAR), Singapore.
Agency for Science, Technology and Research · SGNational Skin Centre · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic and pruritic skin inflammatory disease causing a significant burden to health care management and patient's quality of life. Seemingly healthy skin or non-lesional sites on AD patients still presents skin barrier defects and immune response, which can develop to AD at a later stage. To investigate further the balance between the epidermal barrier impairment and intrinsic immune dysregulation in AD, we exploited multispectral Raster-Scanning Optoacoustic Mesoscopy (ms-RSOM) to image lesional and non-lesional skin areas on AD patients of different severities non-invasively to elucidate their structural features and functional information. Herein, we demonstrate the objective assessment of AD severity using relative changes in oxygen saturation (δsO

Indexed as

Atopic dermatitisEpidermis thicknessMultispectral optoacoustic imagingNon-lesional atopic dermatitisOxygen saturationTotal blood volume

Identifiers

PMID36090012
PMCPMC9450137
OpenAlexW4293340334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.