ArticleMagnetic resonance in medicine2022
NIfTI-MRS: A standard data format for magnetic resonance spectroscopy.
Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 50 citations in OpenAlex.
- Time-Dependent Enhancement of Motor Dexterity and Cerebellar Function via Premotor-Cerebellar Associative Stimulation.The European journal of neuroscience · 2026Article
- A Digital Phantom for MR Spectroscopy Data Simulation.Magnetic resonance in medicine · 2026Article
- DECODE-3DViz: Efficient WebGL-Based High-Fidelity Visualization of Large-Scale Images using Level of Detail and Data Chunk Streaming.Journal of imaging informatics in medicine · 2025Article
- SMART MRS: A Simulated MEGA-PRESS ARTifacts toolbox for GABA-edited MRS.Magnetic resonance in medicine · 2025Article
- MRS-Sim: Open-Source Framework for Simulating In Vivo-Like Magnetic Resonance Spectra.NMR in biomedicine · 2025Article
- MRS-BIDS, an extension to the Brain Imaging Data Structure for magnetic resonance spectroscopy.Scientific data · 2025Article
- Chemical shift and relaxation regularization improve the accuracy ofMagnetic resonance in medicine · 2025Article
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- Macromolecule Modelling for Improved Metabolite Quantification Using Short Echo Time BrainNMR in biomedicine · 2025Article
- Functional magnetic resonance spectroscopy of prolonged motor activation using conventional and spectral GLM analyses.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A graphical pipeline platform for MRS data processing and analysis: MRSpecLAB.Frontiers in neuroimaging · 2025Article
- Brainstem neurochemical profiles after hospitalisation for COVID-19: a 7T MR spectroscopy study.Frontiers in neuroscience · 2025Article
- Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol.Developmental cognitive neuroscience · 2024Article
- Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation.Magnetic resonance in medicine · 2024Article
- Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for advanced MRS.Journal of neuroscience methods · 2024Article
- The relationship between visual acuity loss and GABAergic inhibition in amblyopia.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Universal dynamic fitting of magnetic resonance spectroscopy.Magnetic resonance in medicine · 2024Article
- Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for Advanced MRS.bioRxiv : the preprint server for biology · 2024Article
- Reduction of NIFTI files storage and compression to facilitate telemedicine services based on quantization hiding of downsampling approach.Scientific reports · 2024Article
- Spatiospectral image processing workflow considerations for advanced MR spectroscopy of the brain.Proceedings of SPIE--the International Society for Optical Engineering · 2024Article
Corrections and comments
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Authors and funding
8 authors at 8 institutions in 4 countries.
Funding
Abstract
purposeMultiple data formats in the MRS community currently hinder data sharing and integration. NIfTI-MRS is proposed as a standard spectroscopy data format, implemented as an extension to the Neuroimaging informatics technology initiative (NIfTI) format. This standardized format can facilitate data sharing and algorithm development as well as ease integration of MRS analysis alongside other imaging modalities.
methodsA file format using the NIfTI header extension framework incorporates essential spectroscopic metadata and additional encoding dimensions. A detailed description of the specification is provided. An open-source command-line conversion program is implemented to convert single-voxel and spectroscopic imaging data to NIfTI-MRS. Visualization of data in NIfTI-MRS is provided by development of a dedicated plugin for FSLeyes, the FMRIB Software Library (FSL) image viewer.
resultsOnline documentation and 10 example datasets in the proposed format are provided. Code examples of NIfTI-MRS readers are implemented in common programming languages. Conversion software, spec2nii, currently converts 14 formats where data is stored in image-space to NIfTI-MRS, including Digital Imaging and Communications in Medicine (DICOM) and vendor proprietary formats.
conclusionNIfTI-MRS aims to solve issues arising from multiple data formats being used in the MRS community. Through a single conversion point, processing and analysis of MRS data are simplified, thereby lowering the barrier to use of MRS. Furthermore, it can serve as the basis for open data sharing, collaboration, and interoperability of analysis programs. Greater standardization and harmonization become possible. By aligning with the dominant format in neuroimaging, NIfTI-MRS enables the use of mature tools present in the imaging community, demonstrated in this work by using a dedicated imaging tool, FSLeyes, for visualization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.