Evidence map›Paper›PMID 36089605›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Nutrition support use and clinical outcomes in patients with multiple myeloma undergoing autologous stem cell transplant.

Julia Kuypers, Natalie Simmance, Hang Quach, Katherine Hastie, Nicole Kiss

Abstract read
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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. A liberalized diet does not improve caloric intake during neutropenia in patients undergoing hematopoietic stem cell transplants: A prospective randomized controlled trial.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Trial
  2. Article
  3. Cancers · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Julia KuypersNutrition and Dietetics Department, St Vincent's Hospital, Melbourne, VIC, Australia. Julia.kuypers@svha.org.au.ORCID http://orcid.org/0000-0003-2275-7808
Natalie SimmanceNutrition and Dietetics Department, St Vincent's Hospital, Melbourne, VIC, Australia.
Hang QuachHaematology Department, St Vincent's Hospital Melbourne, Melbourne, VIC, Australia.
Katherine HastieNutrition and Dietetics Department, St Vincent's Hospital, Melbourne, VIC, Australia.
Nicole KissInstitute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, VIC, Australia.
St Vincent's Hospital Melbourne · AUDeakin University · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMalnutrition is associated with worse outcomes post-haematopoietic stem cell transplantation, with nutrition support recommended for people who are malnourished or have prolonged inadequate energy intake. We investigated associations between nutritional status, nutrition support type and clinical outcomes in adults with multiple myeloma post stem cell transplantation.

methodsMedical records (2015-2020) were reviewed to retrieve demographics, anthropometry, dietary data, nutrition support type (enteral/oral versus parenteral), and clinical outcomes (engraftment time, infection, length of stay, weight changes). Relationships were examined using linear regression modelling and Fisher's exact test.

resultsOne hundred thirteen participants were included (61% male; median age 62 years). Fifteen participants (13%) received parenteral and 98 (87%) received enteral/oral nutrition support. Parenteral nutrition was associated with shorter platelet engraftment time by 2.7 days (p = 0.036) and a longer hospital stay by 6.1 days (p < 0.001). Nutrition support was not associated with neutrophil engraftment time (p = 0.365). Inadequate energy intake for ≥ 7 days was not associated with any clinical outcomes (p > 0.05).

conclusionsParticipants who received parenteral nutrition reached platelet engraftment sooner but were in hospital longer. Inadequate energy intake for ≥ 7 days did not impact clinical outcomes. Multi-site prospective studies are warranted to confirm results.

Indexed as

Hematopoietic Stem Cell TransplantationMalnutritionMultiple MyelomaAdultFemaleHumansMaleMiddle AgedNutritional SupportParenteral NutritionStem Cell TransplantationAutologous stem cell transplantEnteral nutritionMultiple myelomaNutrition supportParenteral nutrition

Identifiers

PMID36089605
OpenAlexW4296472224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.