ArticleAnnals of epidemiology2022
Pulmonary hypertension mortality trends in United States 1999-2019.
Article in Annals of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Trial
- Disparity trends in coexisting renal failure- and pulmonary hypertension-related mortality in the United States (1999-2020): CDC WONDER database study.Annals of medicine and surgery (2012) · 2026Article
- Two decades of pulmonary vascular disease and ischemic heart disease mortality in the united states: A longitudinal analysis using CDC WONDER (1999-2020).Journal of thrombosis and thrombolysis · 2026Article
- National Patterns of Pulmonary Hypertension Mortality in the United States, 2010 to 2024.The American journal of cardiology · 2026Article
- The Obstetric Comorbidity Index (OB-CMI) and its association with ICU admission and length of hospital stay in pregnant patients with pulmonary hypertension: a retrospective cohort study (1996-2025).International journal of obstetric anesthesia · 2025Article
- The Impact of Pulmonary Hypertension on Hospitalization Risk in Adults with Respiratory Syncytial Virus Infection.Biomedicines · 2025Article
- Trends in mortality from pulmonary hypertension amongst population with congenital heart disease in the United States from 1999 to 2020: A CDC WONDER analysis.International journal of cardiology. Congenital heart disease · 2025Article
- Opposing roles for myeloid and smooth muscle cell STING in pulmonary hypertension.JCI insight · 2025Article
- Long-term prognostic value of native myocardial tissue relaxation parameters (T1, T2, and T1ρ) in patients with precapillary pulmonary hypertension.The international journal of cardiovascular imaging · 2025Article
- Heart Disease Mortality in the United States, 1970 to 2022.Journal of the American Heart Association · 2025Article
- Mortality and trends of pulmonary arterial hypertension, 1990-2021: a population-based study.Frontiers in cardiovascular medicine · 2025Article
- Glycolysis modulation: New therapeutic strategies to improve pulmonary hypertension (Review).International journal of molecular medicine · 2024Review
- Review
- Exosomes enriched by miR-429-3p derived from ITGB1 modified Telocytes alleviates hypoxia-induced pulmonary arterial hypertension through regulating Rac1 expression.Cell biology and toxicology · 2024Article
- Article
- Pulmonary hypertension leads to poor inpatient outcome in non-white patients admitted with stroke: an analysis of national inpatient sample.Frontiers in stroke · 2024Article
- Article
- Pulmonary hypertension associated mortality in the United States from 2003 to 2020: an observational analysis of time trends and disparities.Journal of thoracic disease · 2023Article
- MicroRNA and lncRNA as the Future of Pulmonary Arterial Hypertension Treatment.International journal of molecular sciences · 2023Review
- Mindfulness meditation for pulmonary hypertension program development: Acceptability and feasibility of technology-assisted complementary health intervention for symptom self-management.Heart & lung : the journal of critical careArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposePulmonary hypertension (PH) is a heterogenous, often progressive disorder leading to right heart failure and death. Previous analyses show stable PH mortality rates from 1980 to 2001 but increasing from 2001 to 2010 especially among women and non-Hispanic (NH) Black. This study seeks to identify recent trends in PH mortality in the United States from 1999 to 2019.
methodsMortality rates among individuals more than or equal to 15 years of age were obtained from the Centers for Disease Control and Prevention's (CDC) Wide-Ranging Online Data for Epidemiology Research (WONDER) database. ICD-10 codes were used to identify individuals with PH.
resultsBetween 1999 and 2019, PH was included as a cause on 429,105 recorded deaths. The average age-adjusted PH mortality rate was 7.9 per 100,000 individuals and increased by 1.9% per year. Higher age-adjusted mortality rates were experienced by females and NH Black persons. The crude mortality rate was 105.4 per 100,000 among those decedents 85 or older. From 1999 to 2019, mortality in PH and left heart disease co-occurrence increased at nearly double the annual rate of the overall PH group.
conclusionsDespite therapeutic advances for selected PH subgroups, the overall age-adjusted PH mortality rate increased significantly from 1999 to 2019 and previously reported racial disparities have persisted. These findings emphasize the need for additional study to improve outcomes in PH.
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