Evidence map›Paper›PMID 36087451›Full record

ArticlePlacenta2022

Change in T2* measurements of placenta and fetal organs during Braxton Hicks contractions.

Esra Abaci Turk, Jeffrey N Stout, Henry A Feldman, Borjan Gagoski, Cindy Zhou, Rubii Tamen, Mary Katherine Manhard, Elfar Adalsteinsson, Drucilla J Roberts, Polina Golland and 2 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Placenta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06290232 (Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06290232 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study

TypeinterventionalSponsorBoston Children's HospitalRan2026 to 2028Enrolled0ConditionsVasa Previa, Pregnancy Complications, Maternal, ProcedureArmsFetoscopic Laser Photocoagulation
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Rapid, high-resolution and distortion-freeMagnetic resonance in medicine · 2025
    Article
  2. Article
  3. Article
  4. TMagnetic resonance in medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Esra Abaci TurkFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: esra.abaciturk@childrens.harvard.edu.
Jeffrey N StoutFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Henry A FeldmanInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Borjan GagoskiFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Cindy ZhouFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Rubii TamenFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Mary Katherine ManhardDepartment of Radiology,Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Elfar AdalsteinssonDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Drucilla J RobertsPathology, Massachusetts General Hospital, Boston, MA, USA.
Polina GollandDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Computer Science and Artificial Intelligence Laboratory (CSAIL), Massachusetts Institute of Technology, Cambridge, MA, USA.
P Ellen GrantFetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
William H BarthMaternal-Fetal Medicine, Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.
Boston Children's Hospital · USMassachusetts General Hospital · USMassachusetts Institute of Technology · USCincinnati Children's Hospital Medical Center · US

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
Fetal MRI: robust self-driving brain acquisition and body movement quantificationR01EB032708 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2022 to 2025
$2.8M
Characterizing the Relationship between Uterine Activity and Placental Function Across Pregnancy with MRIR21HD106553 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ABACI TURK, ESRA · 2022 to 2023
$497k
NIBIB NIH HHS P41 EB015902NIBIB NIH HHS R01 EB032708NICHD NIH HHS P50 HD105351NICHD NIH HHS R01 HD100009NICHD NIH HHS R21 HD106553
6 · The paper itself

Abstract

Maternal-placental perfusion can be temporarily compromised by Braxton Hicks (BH) uterine contractions. Although prior studies have employed T2* changes to investigate the effect of BH contractions on placental oxygen, the effect of these contractions on the fetus has not been fully characterized. We investigated the effect of BH contractions on quantitative fetal organ T2* across gestation together with the birth information. We observed a slight but significant decrease in fetal brain and liver T2* during contractions.

Indexed as

PlacentaUterine ContractionFemaleFetusHumansOxygenPregnancyUterusOxygenBraxton-Hicks contractionFetal organ T2*Placental MRIPlacental T2*T2* mapping

Identifiers

PMID36087451
PMCPMC9674925
OpenAlexW4293473543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.