Evidence map›Paper›PMID 36087377›Full record

Observational studyJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2022

A "Post-mortem" of COVID-19-associated stroke: a case-control study.

Paolo Immovilli, Elena Marchesi, Chiara Terracciano, Nicola Morelli, Veronica Bazzurri, Fabiola Magnifico, Domenica Zaino, Emilio Terlizzi, Paola De Mitri, Stefano Vollaro and 2 more

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Paolo ImmovilliOspedale Guglielmo da Saliceto, Piacenza, Italy. Electronic address: paolo.immovilli.md@gmail.com.
Elena MarchesiOspedale Guglielmo da Saliceto, Piacenza, Italy.
Chiara TerraccianoOspedale Guglielmo da Saliceto, Piacenza, Italy.
Nicola MorelliOspedale Guglielmo da Saliceto, Piacenza, Italy.
Veronica BazzurriOspedale Guglielmo da Saliceto, Piacenza, Italy.
Fabiola MagnificoOspedale Guglielmo da Saliceto, Piacenza, Italy.
Domenica ZainoOspedale Guglielmo da Saliceto, Piacenza, Italy.
Emilio TerlizziOspedale Guglielmo da Saliceto, Piacenza, Italy.
Paola De MitriOspedale Guglielmo da Saliceto, Piacenza, Italy.
Stefano VollaroOspedale Guglielmo da Saliceto, Piacenza, Italy.
Nicola MomettoOspedale Guglielmo da Saliceto, Piacenza, Italy.
Donata GuidettiOspedale Guglielmo da Saliceto, Piacenza, Italy.
Guglielmo da Saliceto Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess whether COVID-19 could be a concurrent factor in the genesis and/or worsening of stroke and to provide data on COVID-19 -associated stroke patients during the first pandemic wave and comparative data on COVID-19 negative stroke patients in the same period. MATERIALS AND

methodsThis is a retrospective, observational, case-control, single centre study, carried out in a General Hospital in northern Italy. Sixty-three consecutive stroke patients were included, COVID-19-associated stroke was classified as cases and non COVID-19-associated stroke as controls.

resultsA total of 19/63 (28.8%) had a COVID-19-associated stroke, 11 /63 (17.5%) were haemorrhagic and 52/63 (82.5%) ischaemic. COVID-19-associated strokes were more severe (p-value 0.019) and had a higher risk of severe disability and/or death (OR 3.79, CI 95%: 1.21-11.93, p-value 0.19). The COVID-19-associated stroke patients with onset during hospitalization for COVID-19 had a more severe stroke than patients with COVID-19 onset during hospitalization for stroke (p-value 0.019).

conclusionAlthough no relationship was observed between the stroke aetiology and COVID-19, intriguingly, COVID-associated stroke turned out to be more severe and disabling. Hopefully, further studies will provide more data and help in the management of this emerging population.

Indexed as

Communicable DiseasesCOVID-19StrokeCase-Control StudiesHumansPandemicsRetrospective StudiesSARS-CoV-2Case-control studyCOVID-19COVID-19-associated strokeLarge vessel occlusionSARS-CoV-2

Identifiers

PMID36087377
PMCPMC9364739
OpenAlexW4290988660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.