ArticleApplied biochemistry and biotechnology2023
Potential Antimicrobial and Antibiofilm Properties of Copper Oxide Nanoparticles: Time-Kill Kinetic Essay and Ultrastructure of Pathogenic Bacterial Cells.
Article in Applied biochemistry and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biogenic Synthesis of Copper Nanoparticles: A Systematic Review of Their Features and Main Applications.Molecules (Basel, Switzerland) · 2023Pooled it
- Advanced Antibacterial Dressings for Chronic Ulcers: Alginate-Collagen-Cotton Hydrogel Composites Functionalized with Green CuO Nanoparticles.Pharmaceutics · 2026Article
- Mytilus edulis-mediated green synthesis of selenium nanoparticles with antimicrobial and molluscicidal applications.Scientific reports · 2026Article
- Copper/Copper Oxide Nanoparticles: Biological Synthesis, Characterization and Potential Biomedical Applications: Advances and Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Design, Synthesis, and Antibiofilm Efficacy of Ag/Se-Doped CuO-Chitosan Nanocomposites as Potent Antifungal Agents Against Candida albicans.Chemistry & biodiversity · 2026Article
- Electrospraying and Nano-Enabled Edible Films for Food Preservation: Controlled Release, Antimicrobial Function, and Future Horizons.Food science & nutrition · 2026Review
- Data-Driven Engineering of Antimicrobial Nanomaterials for Food Safety and Biomedical Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Green synthesis of Ginkgo biloba-mediated magnetite (FeBioprocess and biosystems engineering · 2026Article
- Accelerating wound healing rates with Cucurbita pepo leaf extract loaded electrospun poly(methyl methacrylate)/Halloysite/Chitosan/CaCO₃ composite nanofibers through in vitro and in vivo assessments.Drug delivery and translational research · 2026Article
- Applied Nanobiotechnology for Vector-borne Disease Management: Drug Delivery, Diagnostics, and Sustainable Vector Control.Applied biochemistry and biotechnology · 2026Review
- Antibacterial activity of pelargonium graveolens essential oil nanoemulsion evaluated by microfluidics and DESI mass spectrometry.Scientific reports · 2026Article
- In vitro comparative evaluation of disinfectant-loaded nanoparticles against biofilm-forming Vibrio spp. isolated from gilthead seabream (Sparus aurata).Scientific reports · 2026Article
- Phyto mediated synthesis of copper oxide nanoparticles with Zingiber officinale: comprehensive bioactivity assessment against bacterial pathogens, cancer, and viruses.BMC biotechnology · 2026Article
- Article
- Applications of nanoparticles in plant disease identification and control for sustainable crop production.Discover nano · 2026Review
- Tribological and antibacterial behavior of Cu doped DLC coatings for biomedical implants.Discover materials · 2026Article
- Biosynthesis, Characterization, Antibacterial and Anti-Biofilm Activity of CuO Nanoparticles using Ephedra major Plant Extract againstRecent patents on biotechnology · 2026Article
- Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles.Nanomedicine (London, England) · 2025Article
- Investigating theRSC advances · 2025Article
- Evaluation of eco-friendly copper oxide nanoparticles for anticancer activity and antibacterial effects against Streptococcus mutans using molecular docking.Scientific reports · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycosynthesis of nanoparticle (NP) production is a potential ecofriendly technology for large scale production. In the present study, copper oxide nanoparticles (CuONPs) have been synthesized from the live cell filtrate of the fungus Penicillium chrysogenum. The created CuONPs were characterized via several techniques, namely Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX). Furthermore, the biosynthesized CuONPs were performed against biofilm forming Klebsiella oxytoca ATCC 51,983, Escherichia coli ATCC 35,218, Staphylococcus aureus ATCC 25,923, and Bacillus cereus ATCC 11,778. The anti-bacterial activity result was shown with the zone of inhibition determined to be 14 ± 0.31 mm, 16 ± 0.53 mm, 11 ± 0.57 mm, and 10 ± 0.57 mm respectively. Klebsiella oxytoca and Escherichia coli were more susceptible to CuONPs with minimal inhibitory concentration (MIC) values 6.25 and 3.12 µg/mL, respectively, while for Staphylococcus aureus and Bacillus cereus, MIC value was 12.5 and 25 μg/mL, respectively. The minimum biofilm inhibition concentration (MBIC) result was more evident, that the CuONPs have excellent anti-biofilm activity at sub-MIC levels reducing biofilm formation by 49% and 59% against Klebsiella oxytoca and Escherichia coli, while the results indicated that the MBIC of CuONPs on Bacillus cereus and Staphylococcus aureus was higher than 200 μg/mL and 256 μg/mL, respectively, suggesting that these CuONPs could not inhibit mature formatted biofilm of Bacillus cereus and Staphylococcus aureus in vitro. Overall, all the results were clearly confirmed that the CuONPs have excellent anti-biofilm ability against Klebsiella oxytoca and Escherichia coli. The prepared CuONPs offer a smart approach for biomedical therapy of resistant microorganisms because of its promoted antimicrobial action, but only for specified purposes.
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