Evidence map›Paper›PMID 36086620›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2022

High-performance Flexible Microelectrode Array with PEDOT:PSS Coated 3D Micro-cones for Electromyographic Recording.

Jiaao Lu, Muneeb Zia, Matthew J Williams, Amanda L Jacob, Bryce Chung, Samuel J Sober, Muhannad S Bakir

Abstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. An output-null signature of inertial load in motor cortex.bioRxiv : the preprint server for biology · 2023
    Article
  5. Myomatrix arrays for high-definition muscle recording.bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiaao Lu
Muneeb Zia
Matthew J Williams
Amanda L Jacob
Bryce Chung
Samuel J Sober
Muhannad S Bakir

Funding

Vocal motor control and sensorimotor learning - behavior, muscles, and neuronsR01NS084844 · NINDS · EMORY UNIVERSITY · PI SOBER, SAMUEL · 2013 to 2023
$3.8M
Next-Generation Tools to Measure and Manipulate Muscle Activity Across Species and BehaviorsR01NS109237 · NINDS · EMORY UNIVERSITY · PI Muhannad Bakir, Samuel Sober · 2019 to 2026
$3.8M
Spike timing codes for motor controlR01NS099375 · NINDS · EMORY UNIVERSITY · PI SOBER, SAMUEL · 2017 to 2021
$1.7M
NINDS NIH HHS R01 NS084844NINDS NIH HHS R01 NS099375NINDS NIH HHS R01 NS109237
6 · The paper itself

Abstract

High signal-to-noise ratio (SNR) electromyography (EMG) recordings are essential for identifying and analyzing single motor unit activity. While high-density electrodes allow for greater spatial resolution, the smaller electrode area translates to a higher impedance and lower SNR. In this study, we developed an implantable and flexible 3D microelectrode array (MEA) with low impedance that enables high-quality EMG recording. With polyimide micro-cones realized by standard photolithography process and PEDOT:PSS coating, this design can increase effective surface area by up to 250% and significantly improve electrical performance for electrode sites with various geometric surface areas, where the electrode impedance is at most improved by 99.3%. Acute EMG activity from mice was recorded by implanting the electrodes in vivo, and we were able to detect multiple individual motor units simultaneously and with high resolution ([Formula: see text]). The charge storage capacity was measured to be 34.2 mC/cm

Indexed as

Bridged Bicyclo Compounds, HeterocyclicPolymersAnimalsElectric ImpedanceMiceMicroelectrodesBridged Bicyclo Compounds, Heterocyclicpoly(3,4-ethylene dioxythiophene)Polymers

Identifiers

PMID36086620
PMCPMC10043627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.