Evidence map›Paper›PMID 36086486›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2022

Characterization of a Temporary Peripheral Nerve Stimulation Electrode Utilizing a Bioabsorbable Suture Substrate.

Derrick X Liu, Danny V Lam, Yingyi Gao, Rachel C LeBlanc, Alyssa A Usab, Elizabeth S Fielding, Charlotte L Brunkalla, Kevin Yang, Andrew J Shoffstall

Open access · greenAbstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Derrick X Liu
Danny V Lam
Yingyi Gao
Rachel C LeBlanc
Alyssa A Usab
Elizabeth S Fielding
Charlotte L Brunkalla
Kevin Yang
Andrew J Shoffstall
Case Western Reserve University · USLouis Stokes Cleveland VA Medical Center · US

Funding

The Injectrode - A Truly Injectable Electrode for Dorsal Root Ganglion Stimulation to Treat PainU18EB029251 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI LUDWIG, KIP A, WEBER, DOUGLAS J · 2019 to 2021
$2.5M
NIBIB NIH HHS U18 EB029251RRD VA I01 RX003420
6 · The paper itself

Abstract

Electrical stimulation after peripheral nerve injury (PNI) has the potential to promote more rapid and complete recovery of damaged fiber tracts. While permanently implanted devices are commonly used to treat chronic or persistent conditions, they are not ideal solutions for transient medical therapies due to high costs, increased risk of surgical injury, irritation, infection, and persistent inflammation at the site of the implant. Furthermore, removal of temporary leads placed on or around peripheral nerves may have unacceptable risk for nerve injury, which is counterproductive in developing therapies for PNI treatment. Transient devices which provide effective clinical stimulation while being capable of harmless bioabsorption may overcome key challenges in these areas. However, current bioabsorbable devices are limited in their robustness and require complex fabrication strategies and novel materials which may complicate their clinical translation pathway. In this study, we present a simple bioabsorbable / biodegradable electrode fabricated by modifying standard absorbable sutures, and we present data characterizing our prototype's stability in vitro and in vivo.

Indexed as

Absorbable ImplantsPeripheral Nerve InjuriesElectrodesHumansPeripheral NervesSutures

Identifiers

PMID36086486
PMCPMC10369404
OpenAlexW4294975081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.