Evidence map›Paper›PMID 36085262›Full record

ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2022

Considerations and barriers to starting a new HAI pump program: an international survey of the HAI Consortium Research Network.

Michael Cavnar, Tara Ghalambor, Michael E Lidsky, Ismael Dominguez-Rosado, May Cho, Paul Karanicolas, Ryan Merkow, Skye C Mayo, Flavio G Rocha, Ryan C Fields and 10 more

Abstract read
In one paragraph

Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Michael CavnarDepartment of Surgery, University of Kentucky College of Medicine, 800 Rose St 1st Floor, Lexington, KY 40536, USA.
Tara GhalamborDepartment of Surgery, University of California, Davis, 2279 45th Street, Sacramento, CA 95817, USA.
Michael E LidskyDepartment of Surgery, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC 27707, USA.
Ismael Dominguez-RosadoDepartment of Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Vasco de Quiroga 15, Tlalpan 14000, Mexico City, Mexico.
May ChoDepartment of Medicine, University of California Irvine, 101 The City Dr S, Orange, CA 92868, USA.
Paul KaranicolasDepartment of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, T2-016, Toronto, Ontario M4N 3M5, Canada.
Ryan MerkowDepartment of Surgery, Northwestern University, 675 N Saint Clair, Chicago, IL 60611, USA.
Skye C MayoDepartment of Surgery, Division of Surgical Oncology, Oregon Health & Sciences University, Knight Cancer Institute, 3485 S Bond Ave Building 2, Portland, OR 97239, USA.
Flavio G RochaDepartment of Surgery, Division of Surgical Oncology, Oregon Health & Sciences University, Knight Cancer Institute, 3485 S Bond Ave Building 2, Portland, OR 97239, USA.
Ryan C FieldsDepartment of Surgery, Washington University School of Medicine, 4921 Parkview Pl Suite 12B, St Louis, MO, USA.
Bas G KoerkampDepartment of Surgery, Erasmus MC Cancer Institute, Doctor Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.
Adam YoppDepartment of Surgery, University of Texas Southwestern Medical Center, 2201 Inwood Rd 5th Floor Suite 920, Dallas, TX, USA.
Hendrik PetrowskyDepartment of Surgery and Transplantation, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.
Andrea CercekDepartment of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, NY 10065, USA.
Nancy KemenyDepartment of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, NY 10065, USA.
Peter KinghamDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, 1275 York Avenue, NY 10065, USA.
William JarnaginDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, 1275 York Avenue, NY 10065, USA.
Peter AllenDepartment of Surgery, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC 27707, USA.
Michael D'AngelicaDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, 1275 York Avenue, NY 10065, USA.
Sepideh GholamiDepartment of Surgery, University of California, Davis, 2279 45th Street, Sacramento, CA 95817, USA. Electronic address: sgholami@ucdavis.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundWidespread implementation of HAI pump chemotherapy has been limited by logistic and feasibility concerns. Recent studies demonstrating excellent outcomes have fueled renewed enthusiasm and multiple new programs have emerged. This survey aims to identify barriers critical to establish a successful HAI program.

methodsUsing SurveyMonkey™, a 17-question survey assessing factors required for establishing a successful program was developed by 12 HAI Consortium Research Network (HCRN) surgical oncologists. Content analysis was used to code textual responses. Frequency of categories and average rank scores for each choice were calculated.

resultsTwenty-eight HCRN members responded to the survey. Implementation time varied, with 15 institutions requiring less than a year. Most programs (n = 17) became active in the past 5 years. Medical and surgical oncology were ranked most important for building a program (average ranking scores: 7.96 and 6.59/8). Administrative or regulatory approval was required at half of the institutions. The top 3 challenges faced when building a program were related to regulatory approval (6.65/9), device/equipment access (6.33/9), and drug (FUDR) access (6.25/9).

conclusionDevelopment of successful programs outside of historically established centers is feasible and requires a multidisciplinary team. Future collaborative efforts are critical for sustainability of safe/effective new programs.

Indexed as

Drug TherapyHumansSurveys and Questionnaires

Identifiers

PMID36085262
PMCPMC9771984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.