ArticleHealth and quality of life outcomes2022
EQ-5D-5L measurement properties are superior to EQ-5D-3L across the continuum of health using US value sets.
Article in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
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Who cites it
8 citing papers in PubMed.
- Health-related quality of life in racial and ethnic minority adults with type 2 diabetes: validity and responsiveness of the EQ-5D-3L.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Trial
- Rehabilitation and care after hip fracture: a cost-utility analysis of stepped-wedge cluster randomized trial.Journal of rehabilitation medicine · 2024Trial
- Factor structure and measurement invariance of the EuroQol 5-dimensional questionnaire: a secondary analysis of the Korea Health Panel survey.Osong public health and research perspectives · 2026Article
- Measuring health-related quality of life in multiple sclerosis: comparing the acceptability, validity and responsiveness of the EQ-5D-3L and MSIS-8D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Mapping between EQ-5D-5L and EQ-5D-3L in lumbar spine surgery patients: Machine learning compared to crosswalk algorithms.Brain & spine · 2026Article
- EQ-5D-5L value set for Norway: a hybrid model using cTTO and DCE data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- May the 4th be with you: mixed-methods best-evidence synthesis on 4th-generation alumina-zirconia ceramic bearings in total hip arthroplasty.EFORT open reviews · 2024Article
- The Impacts of COVID-19 Restrictions on Quality Adjusted Life Years (QALY): Heterogeneous effects and post-pandemic recovery.PloS one · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveThe objective of this study was to compare the measurement properties of the US EQ-5D-3L, EQ-5D-5L, and -5L to -3L crosswalk value sets (3L; 5L; 5L > 3L) across the spectrum of health.
methodsThe three scoring approaches were compared in terms of range of scale, percent of worse-than-dead health states, and mean single-level transitions. Discriminative ability was compared by leveraging two cross-sectional datasets. A novel method was used to visualize and compare the responsiveness of 3L and 5L scoring approaches across EQ VAS values.
resultsThe US 5L value set had the broadest range of scale at 1.573 (vs. 1.109 for 3L and crosswalk). The crosswalk had the smallest mean single-level transition of 0.061 (vs. 0.078 for 5L and 0.111 for 3L). The 5L value set tended to be more discriminative/greater statistical efficiency than the crosswalk (F-statistic ratio: 1.111, 95% CI 0.989-1.240) and 3L (F-statistic ratio: 1.102 95% CI 0.861-1.383) across levels of general health. The 5L was the most responsive value set between EQ VAS values of 25 and 75.
conclusionThese results imply greater sensitivity of the 5L to health changes and potentially lower incremental cost-utility ratios compared to the 3L.
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