ArticleOphthalmology. Glaucoma
Comparison of 10-2 and 24-2 Perimetry to Diagnose Glaucoma Using OCT as an Independent Reference Standard.
Article in Ophthalmology. Glaucoma. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Fusing Structural Phenotypes with Functional Data for Early Prediction of Primary Angle-Closure Glaucoma Progression.Ophthalmology science · 2026Article
- Sparse-Observation Multi-Horizon Glaucoma Progression Forecasting with Biologically Constrained Temporal Consistency: A Glaucoma Case Study.Research square · 2026Article
- Accurate Prediction of Humphrey 10-2 Visual Fields in Glaucoma from a Single Rapid IMOvifa 24plus(1-2).Ophthalmology science · 2026Article
- Predicting worsening visual field via masked dual stage attention recurrent neural network.Scientific reports · 2026Article
- Advancements in Visual Field Testing: A Systematic Review of the 24-2C Test Grid.Bioengineering (Basel, Switzerland) · 2025Review
- PyGlaucoMetrics: A Stacked Weight-Based Machine Learning Approach for Glaucoma Detection Using Visual Field Data.Medicina (Kaunas, Lithuania) · 2025Article
- Evaluation of Serum and Aqueous Humor Neurofilament Light Chain as Markers of Neurodegeneration in Glaucoma.Translational vision science & technology · 2025Article
- Transformer-Based Deep Learning Prediction of 10-Degree Humphrey Visual Field Tests From 24-Degree Data.Translational vision science & technology · 2024Article
- Enhancing Detection of Glaucoma Progression: Utility of 24-2 Visual Field Central Points vs. 10-2 Visual Fields.Ophthalmology. GlaucomaObservational
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6 authors.
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Abstract
purposeTo compare the performance of the 10-2 test versus 24-2 standard automated perimetry (SAP) test for the diagnosis of glaucoma using OCT as an independent standard for glaucomatous damage.
designCross-sectional study.
participantsA total of 1375 pairs of 10-2 and 24-2 SAP tests from 569 eyes of 339 subjects were used for the analysis. A total of 440 (77%) eyes had a diagnosis of glaucoma, and 129 (23%) eyes were normal. All participants underwent 10-2 and 24-2 SAP tests within 30 days.
methodsGlaucomatous severity was quantified based on OCT macula ganglion cell layer (mGCL) and circumpapillary retinal nerve fiber layer. The area under the receiver operating characteristic (ROC) curve (AUC) was used to compare 10-2 and 24-2 metrics for discriminating healthy eyes from those of glaucoma, at different levels of disease severity.
main outcome measuresAreas under the ROC curves and sensitivities at fixed specificities of 80% and 95%.
resultsThe overall AUC for mean deviation (MD) for the 24-2 test (0.808) was significantly higher than that of the 10-2 test (0.742; P < 0.001). When compared at different stages of the disease, the 24-2 test performed generally better than the 10-2 test, notably in the earlier stages of the disease. For early damage (first quartile), the 24-2 MD had an AUC of 0.658 versus 0.590 for 10-2 MD (P = 0.018). For advanced damage (fourth quartile), corresponding values were 0.954 vs. 0.903 (P = 0.013). Similar trends were observed when glaucoma severity was defined based on structural macular damage with mGCL thickness.
conclusionsThe 24-2 SAP test had better diagnostic accuracy compared with that of the 10-2 test for detecting equivalent levels of glaucomatous damage, as measured by quantitative assessment of retinal nerve fiber layer and macula by OCT. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references.
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