Evidence map›Paper›PMID 36084794›Full record

ArticleNeuropharmacology2022

Allosteric modulators of the δ GABA

K Genaro, R F Yoshimura, B P Doan, T B Johnstone, D J Hogenkamp, K W Gee

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Modulators of GABANeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

K GenaroDepartment of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, 92697-4625, USA; Department of Anesthesiology, School of Medicine, University of California, Irvine, CA, 92697, USA. Electronic address: kgenaro@hs.uci.edu.
R F YoshimuraDepartment of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, 92697-4625, USA. Electronic address: ryoshimu@uci.edu.
B P DoanDepartment of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, 92697-4625, USA; Department of Anesthesiology, School of Medicine, University of California, Irvine, CA, 92697, USA.
T B JohnstoneDepartment of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, 92697-4625, USA.
D J HogenkampDepartment of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, 92697-4625, USA.
K W GeeDepartment of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, 92697-4625, USA.
University of California, Irvine · US

Funding

Pain drugs based on nicotinic receptor subtype antagonistsR01DA041454 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI GEE, KELVIN W. · 2017 to 2019
$2.3M
NIDA NIH HHS R01 DA041454
6 · The paper itself

Abstract

The present study evaluated the effects of compounds targeting extrasynaptic δ subunit-containing γ-aminobutyric acid type A receptors (δ*-GABA

Indexed as

Analgesics, OpioidMorphineAnalgesicsAnimalsDose-Response Relationship, DrugFemalegamma-Aminobutyric AcidHumansMaleMiceMice, KnockoutReceptors, GABA-AReceptors, Opioid, deltaWaterAnalgesicsAnalgesics, Opioidgamma-Aminobutyric AcidMorphineReceptors, GABA-AReceptors, Opioid, deltaWaterMorphine-antinociceptive toleranceOpioidOpioid withdrawal symptomsPositive allosteric modulatorsδ-subunit GABA(A) receptor

Identifiers

PMID36084794
PMCPMC11012237
OpenAlexW4295940668

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.