ArticlePloS one2022
Body mass index and physical frailty among older Mexican Americans: Findings from an 18-year follow up.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- The impact of BMI on mechanical thrombectomy outcomes, insights from a comprehensive stroke center.Neurosurgical review · 2026Article
- Gender-specific sociodemographic and lifestyle factors associated with frailty status among Korean older adults.PloS one · 2026Article
- The iceberg of frailty: underlying mechanisms beyond self-reported weight trajectories.Aging clinical and experimental research · 2025Article
- The Effect of Frailty on Body Composition and Its Impact on the Use of SGLT-2 Inhibitors and GLP-1RA in Older Persons with Diabetes.Metabolites · 2025Review
- Body mass index and trajectories of muscle strength and physical function over time in Mexican American older adults: Sex differences.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025Article
- Development and validation of PRE-FRA (PREdiction of FRAilty risk in community older adults) frailty prediction model.Frontiers in public health · 2025Article
- A pilot study to identify factors associated with frailty within the World Trade Center general responder cohort.American journal of industrial medicine · 2024Article
- Vision Impairment and Frailty Among Mexican American Older Adults: A Longitudinal Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Article
- Frailty and the Interactions between Skeletal Muscle, Bone, and Adipose Tissue-Impact on Cardiovascular Disease and Possible Therapeutic Measures.International journal of molecular sciences · 2023Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposesThe relationship between body mass index (BMI) and frailty in older Mexican Americans has not been previously studied. The objective of this study was to examine the relationship between BMI and frailty among non-frail older Mexican Americans at baseline over 18 years of follow up.
methodsLongitudinal population-based study of 1,648 non-institutionalized Mexican Americans aged ≥ 67 years from the Hispanic Established Population for the Epidemiologic Study of the Elderly (1995/96-2012/13). Frailty phenotype was defined as meeting three or more of the following: unintentional weight loss of >10 pounds, weakness, self-reported exhaustion, low physical activity, and slow walking speed. BMI (kg/m2) was classified as underweight (<18.5), normal weight (18.5-<25), overweight (25-< 30), obesity category I (30-<35), and obesity category II/morbid obesity (≥35). Covariates included socio-demographics, comorbidities, cognitive function, and depressive symptoms. Generalized Estimating Equation models were performed to estimate the odds ratio (OR) and 95% confidence interval (CI) of frailty as a function of BMI category.
resultsParticipants with underweight or obesity category II/ morbid obesity had greater odds of frailty over time compared to those with normal weight (OR = 2.39, 95% CI = 1.29-4.44 and OR = 1.62, 95% CI = 1.07-2.44, respectively) after controlling for all covariates. Participants with BMIs in the overweight or category I obesity were at lower odds of frailty over time.
conclusionsMexican American older adults with BMIs in the underweight or obesity category II/morbid obesity were at higher odds of frailty over time. This indicates that maintaining a healthy weight in this population may prevent future frailty.
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