Evidence map›Paper›PMID 36083486›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2022

Electroacupuncture attenuates chronic salpingitis transforming growth factor-β1/p38 mitogen-activated protein kinase signaling pathway.

H U Xijiao, Cheng Yinglong, Kang Huanan, L I Shuoxi, Wang Yawen, Liu Jinzhe, Sun Yiming, Liu Li

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

H U XijiaoDepartment of obstetrics and gynecology, the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang 150001, China.
Cheng YinglongDeapartment of Hysteroscopy chamber, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Kang HuananCollege of pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
L I ShuoxiMidwifery Teaching and Research Section, Heilongjiang University of Chinese Medicine Jiamusi College, Harbin 150040, China.
Wang YawenThe department of obstetrics and gynecology, the First Affiliated Hospital of Henan University of Chinese Medicine, Henan 450000, China.
Liu JinzheDepartment of Chinese Pharmacy, School of Pharmacy, Guizhou University of Chinese Medicine, Guizhou 550000, China.
Sun YimingAndrology department Heilongjiang Academy of Traditional Chinese Medicine, Harbin 150036, China.
Liu LiEndoscopy room, the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Hysteroscopy Department, Harbin 150040, China.
Heilongjiang University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effect of electroacupuncture (EA) on rats with chronic fallopian tube inflammation and its potential mechanisms.

methodsThirty-six female Sprague-Dawley rats were divided into Control, Model and EA groups. The pathological morphology of the fallopian tubes was observed by hematoxylin-eosin (HE) and Masson staining. The results of transforming growth factor-β1 (TGF-β1), P38 mitogen-activated protein kinase (MAPK), phosphorylation (p)-p38MAPK in rat oviduct tissues were detected by immunohistochemistry. Results of P38MAPK, p-P38MAPK and TGF-β1 in rat oviduct tissues were detected by immunofluorescence. The expression level of p38MAPK, p-P38MAPK, TGF-β1 protein in rats was detected by Western blot. Quantitative real-time polymerase chain reaction (RT-qPCR) was used to detect mRNA expression levels of TGF-β1.

resultsIt found that collagen fibers counts decreased significantly in EA group compared to Model group. The phosphorylation of P38MAPK in EA group was significantly reduced compared to Model group. The serum TGF-β1 expressions in EA group increased decreased significantly.

conclusionElectroacupuncture was able to attenuate chronic salpingitis through down-regulating TGF-β1/MAPK signaling pathway.

Indexed as

ElectroacupunctureSalpingitisAnimalsFemaleHumansp38 Mitogen-Activated Protein KinasesRatsRats, Sprague-DawleySignal TransductionTransforming Growth Factor beta1p38 Mitogen-Activated Protein KinasesTransforming Growth Factor beta1electroacupuncturemitogen-activated protein kinasesalpingitistransforming growth factor beta1

Identifiers

PMID36083486
PMCPMC9924660
OpenAlexW4295078815

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.