Evidence map›Paper›PMID 36083345›Full record

ArticleAmino acids2022

Branched-chain amino acids regulate intracellular protein turnover in porcine mammary epithelial cells.

Reza Rezaei, Guoyao Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Amino acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Characteristics of Nutrition and Metabolism in Dogs and Cats.Advances in experimental medicine and biology · 2024
    Article
  5. Dietary supplementation withFrontiers in veterinary science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Reza RezaeiDepartment of Animal Science, Texas A&M University, College Station, Texas, 77843, USA.
Guoyao WuDepartment of Animal Science, Texas A&M University, College Station, Texas, 77843, USA. g-wu@tamu.edu.ORCID http://orcid.org/0000-0001-8058-6969
Texas A&M University · US

Funding

Texas A&M AgriLife Research H-8200
6 · The paper itself

Abstract

Dietary supplementation with branched-chain amino acids (BCAAs) to lactating sows has been reported to enhance their milk production, but the underlying mechanisms remain largely unknown. This study was conducted with porcine mammary epithelial cells (PMECs) to test the hypothesis that individual BCAAs or their mixture stimulates protein synthesis and inhibit proteolysis in PMECs. Cells were cultured at 37 °C in customized Dulbecco's modified Eagle medium containing 5 mmol/L D-glucose, 1 mmol/L L-phenylalanine, L-[ring-2,4-

Indexed as

Amino Acids, Branched-ChainMammary Glands, AnimalAnimalsCaseinsEpithelial CellsFemaleIsoleucineLactationLeucineProteasome Endopeptidase ComplexProteolysisSwineTOR Serine-Threonine KinasesUbiquitinValineAmino Acids, Branched-ChainCaseinsIsoleucineLeucineProteasome Endopeptidase ComplexTOR Serine-Threonine KinasesUbiquitinValineIsoleucineLactationLeucineNutritionPigsProtein turnoverValine

Identifiers

PMID36083345
OpenAlexW4295079371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.