Evidence map›Paper›PMID 36082932›Full record

ArticleActa biochimica et biophysica Sinica2022

Genipin improves lipid metabolism and sperm parametersin obese mice via regulation of miR-132 expression.

Li Wang, Ge Chen, Shuyao Wu, Yihua Xu, Chenxi Guo, Manman Wang, Tingming Liang, Zhigang Guo, Hong-Jie Di, Zhigang Hu

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Li WangJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Ge ChenJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Shuyao WuJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Yihua XuJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Chenxi GuoDepartment of Endocrinology, the Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing210017, China.
Manman WangDepartment of Endocrinology, the Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing210017, China.
Tingming LiangJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Zhigang GuoJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Hong-Jie DiDepartment of Endocrinology, the Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing210017, China.
Zhigang HuJiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210023, China.
Nanjing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity has now surpassed malnutrition and infectious diseases as the most significant contributor to health problems worldwide. In particular, obesity is associated with several metabolic disorders, including hyperlipidemia, hepatic steatosis, and subfertility. Genipin (GNP), the aglycone of geniposide, is isolated from the extract of the traditional Chinese medicine

Indexed as

Fatty LiverHyperlipidemiasMetabolic DiseasesMicroRNAsAnimalsDiet, High-FatIridoidsLipid MetabolismLiverMaleMiceMice, Inbred C57BLMice, ObeseObesitySemenSpermatozoagenipinIridoidsMicroRNAsMIRN132 microRNA, mouseSterol Regulatory Element Binding Protein 1genipinmetabolic disordermiR-132obesitysperm function

Identifiers

PMID36082932
PMCPMC9827900
OpenAlexW4293090335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.