ArticleInfection control and hospital epidemiology2022
Hospital-onset bacteremia and fungemia: An evaluation of predictors and feasibility of benchmarking comparing two risk-adjusted models among 267 hospitals.
Article in Infection control and hospital epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 29 citations in OpenAlex.
- Variability in Hospital-Onset Bacteremia in Ontario.JAMA network open · 2026Article
- National automated surveillance of hospital onset bacteraemia and fungaemia using data from the national antimicrobial resistance surveillance system: a retrospective exploratory evaluation, the Netherlands, 2018 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- Hospital-Onset Bloodstream Infections: Progressive Shift from Methicillin-ResistantJournal of clinical medicine · 2026Article
- Advancing hospital-onset bacteraemia surveillance: a five-year retrospective study following the hospital-wide implementation of an automated surveillance system at a German university hospital.Antimicrobial resistance and infection control · 2026Article
- The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Letter to the editor: Towards effective implementation of hospital-onset bacteraemia and fungaemia as a quality metric.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Multicenter evaluation of blood culture contamination and blood cultures practices in US acute care hospitals: time for standardization.Journal of clinical microbiology · 2025Article
- Integrating Nonindividual Patient Features in Machine Learning Models of Hospital-Onset Bacteremia.JAMA network open · 2025Article
- Hospital-onset bacteraemia and fungaemia as a novel automated surveillance indicator: results from four European university hospitals, 2018 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Observational
- Automated surveillance of hospital-onset bacteremia and fungemia: feasibility and epidemiological results from a Dutch multicenter study.Infection control and hospital epidemiology · 2025Article
- Catheter-associated urinary tract infections (CAUTIs) and non-CAUTI hospital-onset urinary tract infections: Relative burden, cost, outcomes and related hospital-onset bacteremia and fungemia infections.Infection control and hospital epidemiology · 2024Observational
- Epidemiology and preventability of hospital-onset bacteremia and fungemia in 2 hospitals in India.Infection control and hospital epidemiology · 2024Article
- Treated, hospital-onsetInfection control and hospital epidemiology · 2024Article
- Trends and outcomes in community-onset and hospital-onsetAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Characteristics, costs, and outcomes associated with central-line-associated bloodstream infection and hospital-onset bacteremia and fungemia in US hospitals.Infection control and hospital epidemiology · 2023Observational
- Direct-from-Blood Detection of Pathogens: a Review of Technology and Challenges.Journal of clinical microbiology · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the prevalence of hospital-onset bacteremia and fungemia (HOB), identify hospital-level predictors, and to evaluate the feasibility of an HOB metric.
methodsWe analyzed 9,202,650 admissions from 267 hospitals during 2015-2020. An HOB event was defined as the first positive blood-culture pathogen on day 3 of admission or later. We used the generalized linear model method via negative binomial regression to identify variables and risk markers for HOB. Standardized infection ratios (SIRs) were calculated based on 2 risk-adjusted models: a simple model using descriptive variables and a complex model using descriptive variables plus additional measures of blood-culture testing practices. Performance of each model was compared against the unadjusted rate of HOB.
resultsOverall median rate of HOB per 100 admissions was 0.124 (interquartile range, 0.00-0.22). Facility-level predictors included bed size, sex, ICU admissions, community-onset (CO) blood culture testing intensity, and hospital-onset (HO) testing intensity, and prevalence (all
conclusionsHospital descriptors, aggregate patient characteristics, community bacteremia and/or fungemia burden, and clinical blood-culture testing practices influence rates of HOB. Benchmarking an HOB metric is feasible and should endeavor to include both facility and clinical variables.
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