ArticleInfection control and hospital epidemiology2023
Risk and protective factors for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among healthcare workers: A test-negative case-control study in Québec, Canada.
Article in Infection control and hospital epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Differential Odds of COVID-19 Infection Associated With Household and Workplace Exposures in US Health Care Personnel.Journal of occupational and environmental medicine · 2026Article
- Is COVID-19 Associated With an Increased Risk of Subsequent Upper Respiratory Tract Infections in Adults? A Prospective Cohort Study.Open forum infectious diseases · 2025Article
- Article
- SARS-CoV-2 Infection Among Nursing Home Healthcare Workers: A Longitudinal Study in North-Eastern Italy.Influenza and other respiratory viruses · 2024Article
- Risk of Testing Positive for COVID-19 among Healthcare and Healthcare-Related Workers.Vaccines · 2023Article
- SARS-CoV-2 infection among healthcare workers: the role of occupational and household exposures during the first three pandemic waves in Quebec, Canada.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
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Authors and funding
12 authors.
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Abstract
objectivesIn Québec, Canada, we evaluated the risk of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection associated with (1) the demographic and employment characteristics among healthcare workers (HCWs) and (2) the workplace and household exposures and the infection prevention and control (IPC) measures among patient-facing HCWs.
designTest-negative case-control study.
settingProvincial health system.
participantsHCWs with PCR-confirmed coronavirus disease 2019 (COVID-19) diagnosed between November 15, 2020, and May 29, 2021 (ie, cases), were compared to HCWs with compatible symptoms who tested negative during the same period (ie, controls).
methodsAdjusted odds ratios (aORs) of infection were estimated using regression logistic models evaluating demographic and employment characteristics (all 4,919 cases and 4,803 controls) or household and workplace exposures and IPC measures (2,046 patient-facing cases and 1,362 controls).
resultsCOVID-19 risk was associated with working as housekeeping staff (aOR, 3.6), as a patient-support assistant (aOR, 1.9), and as nursing staff (aOR, 1.4), compared to administrative staff. Other risk factors included being unexperienced (aOR, 1.5) and working in private seniors' homes (aOR, 2.1) or long-term care facilities (aOR, 1.5), compared to acute-care hospitals. Among patient-facing HCWs, exposure to a household contact was reported by 9% of cases and was associated with the highest risk of infection (aOR, 7.8). Most infections were likely attributable to more frequent exposure to infected patients (aOR, 2.7) and coworkers (aOR, 2.2). Wearing an N95 respirator during contacts with COVID-19 patients (aOR, 0.7) and vaccination (aOR, 0.2) were the measures associated with risk reduction.
conclusionIn the context of the everchanging SARS-CoV-2 virus with increasing transmissibility, measures to ensure HCW protection, including vaccination and respiratory protection, and patient safety will require ongoing evaluation.
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