Evidence map›Paper›PMID 36082466›Full record

ArticleJournal of clinical laboratory analysis2022

Effects of co-infection with Clonorchis sinensis on the sex hormones levels in male patients with chronic hepatitis B.

Huimin Dong, Mei Shang, Minqi Luo, Wenya Chen, Bo Hu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huimin DongDepartment of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-5975-6094
Mei ShangDepartment of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Minqi LuoDepartment of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wenya ChenDepartment of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Bo HuDepartment of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CN

Funding

Guangzhou Science and technology project 202201020417National Natural Science Foundation of China 81902082
6 · The paper itself

Abstract

objectiveWe evaluated the levels of sex hormones in male hepatitis B patients co-infected with Clonorchis sinensis (C. sinensis).

methodsA total of 136 male individuals were enrolled in this study, including 27 healthy controls, 28 patients with C. sinensis mono-infection, 19 patients with only chronic hepatitis B, 18 patients with post-hepatitis B liver cirrhosis, 26 chronic hepatitis B patients co-infected with C. sinensis, and 18 post-hepatitis B liver cirrhosis patients coinfected with C. sinensis. Serum levels of progesterone (P), luteinizing hormone (LH), estradiol (E2), testosterone (T), prolactin (PRL), and follicle stimulating hormone (FSH) in these groups were measured.

resultsThe results showed that compared with the LC group, the LC

conclusionThis study suggests that C. sinensis co-infection aggravates the sex hormone disturbance in HBV patients at both chronic hepatitis and cirrhosis stages, providing evidences for potential strategies in disease prevention and treatment.

Indexed as

Clonorchis sinensisCoinfectionHepatitis BHepatitis B, ChronicAnimalsFollicle Stimulating HormoneGonadal Steroid HormonesHumansLiver CirrhosisMaleProlactinFollicle Stimulating HormoneGonadal Steroid HormonesProlactinchronic hepatitis BClonorchis sinensisco-infectionpost-hepatitis B liver cirrhosis

Identifiers

PMID36082466
PMCPMC9459257
OpenAlexW4292181284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.