Evidence map›Paper›PMID 36082407›Full record

ArticleAmerican journal of men's health

Expression Analysis of miRNAs and Their Potential Role as Biomarkers for Prostate Cancer Detection.

Fernando Bergez-Hernández, Eliakym Arámbula-Meraz, Marco Alvarez-Arrazola, Martín Irigoyen-Arredondo, Fred Luque-Ortega, Alejandra Martínez-Camberos, Dora Cedano-Prieto, José Contreras-Gutiérrez, Carmen Martínez-Valenzuela, Noemí García-Magallanes

Abstract read
In one paragraph

Article in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fernando Bergez-HernándezPosgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.
Eliakym Arámbula-MerazLaboratorio de Genética y Biología Molecular, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.
Marco Alvarez-ArrazolaAlvarez & Arrazola Radiólogos, Mazatlán, México.
Martín Irigoyen-ArredondoPosgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.
Fred Luque-OrtegaLaboratorio de Ciencias Básicas, Facultad de Odontología, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.ORCID 0000-0002-6295-1958
Alejandra Martínez-CamberosPosgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.
Dora Cedano-PrietoLaboratorio de Genética y Biología Molecular, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.
José Contreras-GutiérrezCentro de Investigación y Docencia en Ciencias de la Salud, Hospital Civil de Culiacán, Universidad Autónoma de Sinaloa, Culiacán Rosales, México.
Carmen Martínez-ValenzuelaLaboratorio de Genotoxicología "Dr Jesus Kumate Rodriguez," Unidad de Investigación en Ambiente y Salud, Universidad Autónoma de Occidente, Los Mochis, México.
Noemí García-MagallanesLaboratorio de Biomedicina y Biología Molecular, Ingeniería en Biotecnología, Universidad Politécnica de Sinaloa, Mazatlán, México.ORCID 0000-0001-8442-2873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is the second most frequent cancer diagnosed in men worldwide. The detection methods for PCa are either unreliable, like prostate-specific antigen (PSA), or extremely invasive, such as in the case of biopsies. Therefore, there is an urgent necessity for reliable and less invasive detection procedures that can differentiate between patients with benign diseases and those with cancer. In this matter, microRNAs (miRNAs) are suggested as potential biomarkers for cancer. MiRNAs have been found to be dysregulated in several different cancers, and these genetic alterations may present specific signatures for a given malignancy. Here, we examined the expression of miR141-3p, miR145-5p, miR146a-5p, and miR148b-3p in human tissue samples of PCa (

Indexed as

MicroRNAsProstatic NeoplasmsBiomarkers, TumorBiopsyHumansMaleProstateBiomarkers, TumorMicroRNAsMIRN145 microRNA, humanbiomarkersexpressionmiRNAspredicted modelprostate cancer

Identifiers

PMID36082407
PMCPMC9465588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.