Evidence map›Paper›PMID 36082283›Full record

ArticleArthroplasty today2022

Total Joint Arthroplasty Should Not Be Delayed in Hepatitis C Patients After Successful Treatment Achieving a Sustained Viral Load.

Kyle H Cichos, Eric Jordan, Kian Niknam, Antonia F Chen, Erik N Hansen, Gerald McGwin, Elie S Ghanem

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthroplasty today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Note From the Editor.Arthroplasty today · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kyle H CichosDepartment of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Eric JordanDepartment of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Kian NiknamDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA.
Antonia F ChenDepartment of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Erik N HansenDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA.
Gerald McGwinDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Elie S GhanemDepartment of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USBrigham and Women's Hospital · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preoperative treatment recommendations and optimal time to perform total joint arthroplasty (TJA) in patients with hepatitis C virus after treatment completion for achieving best outcomes have not been elucidated. We aim to determine (1) if undetectable viral load (UVL) prior to TJA leads to decreased postoperative complication rates, specifically periprosthetic joint infection (PJI), and (2) if delaying TJA after treatment completion has benefit in decreasing PJI. Methods: A retrospective review of all hepatitis C virus patients undergoing TJA at 3 academic tertiary care centers was conducted. A total of 270 TJAs performed from 2005 to 2019 were included, 125 with positive viral load at the time of surgery. The duration from completion of treatment regimen to TJA was recorded for the UVL cohort. The primary study outcome was PJI at 1-year follow-up. Secondary outcomes included in-hospital complications, mechanical revision TJA rates, and optimal time to TJA upon completion of treatment. Results: Patients with positive viral load at the time of TJA had longer length of stay (3.9 vs 2.9 days, Conclusions: Sustained UVL prior to TJA is critical to minimize PJI irrespective of the treatment regimen utilized. Surgery can be performed with lower complication rates any time after achieving sustained virologic response. Level of Evidence: Level III, prognostic retrospective cohort study.

Indexed as

Hepatitis COutcomesPeriprosthetic joint infectionTotal joint arthroplastyTreatmentViral load level

Identifiers

PMID36082283
PMCPMC9445225
OpenAlexW4293490639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.