Evidence map›Paper›PMID 36082280›Full record

ArticleJTO clinical and research reports2022

A Real-World Analysis of Immune Checkpoint Inhibitor-Based Therapy After Osimertinib Treatment in Patients With

Kenji Morimoto, Ryo Sawada, Tadaaki Yamada, Koichi Azuma, Kentaro Ito, Yasuhiro Goto, Hideharu Kimura, Taishi Harada, Shinsuke Shiotsu, Nobuyo Tamiya and 8 more

Abstract read
In one paragraph

Article in JTO clinical and research reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kenji MorimotoDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ryo SawadaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tadaaki YamadaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Koichi AzumaDivision of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Fukuoka City, Japan.
Kentaro ItoRespiratory Center, Matsusaka Municipal Hospital Respiratory Center, Matsusaka, Japan.
Yasuhiro GotoDepartment of Respiratory Medicine, Fujita Health University of Medicine, Aichi, Japan.
Hideharu KimuraRespiratory Medicine, Kanazawa University Hospital, Ishikawa, Japan.
Taishi HaradaDepartment of Medical Oncology, Fukuchiyama City Hospital, Kyoto, Japan.
Shinsuke ShiotsuDepartment of Respiratory Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan.
Nobuyo TamiyaDepartment of Pulmonary Medicine, Rakuwakai Otowa Hospital, Kyoto, Japan.
Yusuke ChiharaDepartment of Respiratory Medicine, Uji-Tokushukai Medical Center, Kyoto, Japan.
Takayuki TakedaDepartment of Respiratory Medicine, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
Osamu HiranumaDepartment of Pulmonary Medicine, Otsu City Hospital, Shiga, Japan.
Isao HasegawaDepartment of Pulmonary Medicine, Saiseikai Shiga Hospital, Shiga, Japan.
Yoshie MorimotoDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Masahiro IwasakuDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Shinsaku TokudaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Koichi TakayamaDepartment of Pulmonary Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The use of immune checkpoint inhibitors (ICIs) with chemotherapy has increased the survival of patients with advanced NSCLC. Nevertheless, the efficacy of ICI treatment for NSCLC with Methods: This study performed a retrospective analysis of the association between clinical characteristics and ICI efficacy in patients with Results: Among 80 patients with Conclusions: The PFS of osimertinib might be a predictor of PFS of chemoimmunotherapy in patients with

Indexed as

ChemoimmunotherapyEGFR mutationImmune checkpoint inhibitorNon–small cell lung cancerOsimertinib

Identifiers

PMID36082280
PMCPMC9445370

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.