Evidence map›Paper›PMID 36082208›Full record

ArticleCardiology research and practice2022

Synthesized 18-Lead Electrocardiogram in Diagnosing Posterior Stemi-Equivalent Acute Coronary Syndrome in Patients with NSTEMI.

Tomoki Horie, Rikuta Hamaya, Tomoyo Sugiyama, Hidenori Hirano, Masahiro Hoshino, Yoshihisa Kanaji, Tetsumin Lee, Taishi Yonetsu, Tetsuo Sasano, Tsunekazu Kakuta

Open access · goldAbstract read
In one paragraph

Article in Cardiology research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Evidence for Electrocardiographic Patterns Identifying Acute Coronary Occlusion in Non-ST-Elevation Acute Coronary Syndromes: A Scoping Review.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tomoki HorieDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.ORCID https://orcid.org/0000-0002-5378-4422
Rikuta HamayaDivision of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Tomoyo SugiyamaDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Hidenori HiranoDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Masahiro HoshinoDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Yoshihisa KanajiDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Tetsumin LeeDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.
Taishi YonetsuDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Tetsuo SasanoDepartment of Cardiovascular Medicine, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Tsunekazu KakutaDepartment of Cardiology, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.ORCID https://orcid.org/0000-0002-4004-5292
Tsuchiura Kyodo General Hospital · JPTokyo Medical and Dental University · JPBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the clinical utility of synthesized V7-V9 ST-segment elevation (sV7-9 STE) in patients with 12-lead-electrocardiogram (ECG)-based non-STE myocardial infarction (NSTEMI) in diagnosing left circumflex artery (LCx) STEMI-equivalent acute coronary syndrome (ACS). Background: The 12-lead-ECG is insufficient for diagnosing patients with ACS, especially those with an LCx culprit. Methods: We retrospectively examined 219 patients with NSTEMI who underwent synthesized 18-lead ECG acquisition on admission and urgent catheterization. Associations between baseline variables, including sV7-9 STE and LCx STEMI-equivalent ACS, were analyzed using logistic regression models and receiver operating characteristics. LCx-culprit ACS was defined as thrombolysis in myocardial infarction (TIMI) 0-1 flow. The association between sV7-9 STE and myocardial damage was also assessed. Results: The mean (SD) age of the population was 68.8 (12.0) years, and 81.7% were men. LCx-culprit NSTEMI occurred in 58 (26.5%) patients and 15 (6.8%) were LCx STEMI-equivalent. SV7-9 STE was observed in 16 patients (7.9%). SV7-9 STE was the sole significant predictor of LCx STEMI-equivalent ACS with an odds ratio of 19.0 (95% CI: 5.6-63.9, Conclusions: SV7-9 STE had sole preprocedural diagnostic utility in detecting LCx STEMI-equivalent ACS with greater myocardial damage among patients with 12 ECG-based NSTEMI. The use of synthesized extra leads on admission may help identify patients with NSTEMI requiring primary revascularization.

Identifiers

PMID36082208
PMCPMC9448611
OpenAlexW4292180755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.