Evidence map›Paper›PMID 36082183›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Qiliqiangxin Capsule Modulates Calcium Transients and Calcium Sparks in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Yuxin Li, Zhang Zhang, Xuezeng Hao, Tingting Yu, Sen Li

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuxin LiSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Zhang ZhangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Xuezeng HaoDongzhimen Hospital of Beijing University of Chinese Medicine, Beijing, China.
Tingting YuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Sen LiSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0003-4496-5050
Beijing University of Chinese Medicine · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The therapeutic effects of Qiliqiangxin capsule (QLQX), a Chinese patent medicine, in patients with chronic heart failure are well established. However, whether QLQX modulates cardiac calcium (Ca Materials and Methods: Fluorescence imaging was used to monitor Ca Results: The QLQX treatment substantially decreased the frequency of spontaneous Ca Conclusions: Our findings provide the first line of evidence that QLQX directly modulates cardiac Ca

Identifiers

PMID36082183
PMCPMC9448542
OpenAlexW4293860386

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.