ArticleFrontiers in bioengineering and biotechnology2022
Ligament mechanics of ageing and osteoarthritic human knees.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Predicted effects of hip distraction on knee ligament mechanics following total knee arthroplasty: A finite element analysis.Clinical biomechanics (Bristol, Avon) · 2026Article
- A Novel Concept of Tissue Micro-Instability as the Underlying Mechanism of Osteophytosis in Human Knee Osteoarthritis.Biomedicines · 2026Article
- Article
- The correlation between femoral trochlear dysplasia and meniscal tear in young individuals: a finite element analysis based on MRI.Quantitative imaging in medicine and surgery · 2025Article
- Risk factors of patellofemoral instability in patients with hypermobile Ehlers-Danlos syndrome.Archives of orthopaedic and trauma surgery · 2025Article
- Contributions of External, Muscle, and Ligament Forces to Tibiofemoral Contact Loads in Patients with Knee Osteoarthritis and Healthy Individuals.Bioengineering (Basel, Switzerland) · 2025Article
- Development of a personalized parametric finite element model of the knee: Evaluation of geometric variables affecting osteoarthritis progression.Journal of orthopaedics · 2025Article
- How Strong Is the Ligamentum Teres of the Hip? A Biomechanical Analysis.Clinical orthopaedics and related research · 2024Article
- Understanding the Structure-Function Relationship through 3D Imaging and Biomechanical Analysis: A Novel Methodological Approach Applied to Anterior Cruciate Ligaments.Biomimetics (Basel, Switzerland) · 2024Article
- Model Properties and Clinical Application in the Finite Element Analysis of Knee Joint: A Review.Orthopaedic surgery · 2024Review
- Creep-recovery behaviors of articular cartilage under uniaxial and biaxial tensile loadings.Frontiers in bioengineering and biotechnology · 2022Article
- Proteoglycans play a role in the viscoelastic behaviour of the canine cranial cruciate ligament.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Knee joint ligaments provide stability to the joint by preventing excessive movement. There has been no systematic effort to study the effect of OA and ageing on the mechanical properties of the four major human knee ligaments. This study aims to collate data on the material properties of the anterior (ACL) and posterior (PCL) cruciate ligaments, medial (MCL) and lateral (LCL) collateral ligaments. Bone-ligament-bone specimens from twelve cadaveric human knee joints were extracted for this study. The cadaveric knee joints were previously collected to study ageing and OA on bone and cartilage material properties; therefore, combining our previous bone and cartilage data with the new ligament data from this study will facilitate subject-specific whole-joint modelling studies. The bone-ligament-bone specimens were tested under tensile loading to failure, determining material parameters including yield and ultimate (failure) stress and strain, secant modulus, tangent modulus, and stiffness. There were significant negative correlations between age and ACL yield stress (
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