Evidence map›Paper›PMID 36082121›Full record

ReviewFrontiers in cardiovascular medicine2022

Evaluation of race and ethnicity disparities in outcome studies of

Anh B Nguyen, Larisa H Cavallari, Joseph S Rossi, George A Stouffer, Craig R Lee

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06665919 (Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06665919 nacompletednot on this mapstarted 2023, after this paper: background citation

Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI

TypeinterventionalSponsorVistamedi Ltd.Ran2023 to 2025Enrolled283ConditionsCoronary Artery Disease, Clopidogrel Resistance, Coronary Thrombosis, Adverse Cardiac EventsArmsCYP2C19 Genotype-Guided Clopidogrel Treatment, CYP2C19 Genotype Guided Antiplatelet Treatment Alternative to Clopidogrel, The Conventional Clopidogrel Treatment
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Distribution ofFrontiers in genetics · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Prevalence ofPharmacogenomics and personalized medicine · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Association ofBalkan journal of medical genetics : BJMG · 2024
    Article
  14. Article
  15. Genetic Determinants of Response to P2YInterventional cardiology clinics · 2024
    Review
  16. Genotype-Guided Antiplatelet Therapy: JACC Review Topic of the Week.Journal of the American College of Cardiology · 2024
    Review
  17. Circulation · 2024
    Review
  18. Article
  19. Article
  20. Journal of the American Heart Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anh B NguyenDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Larisa H CavallariDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, United States.
Joseph S RossiDivision of Cardiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
George A StoufferDivision of Cardiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Craig R LeeDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
University of North Carolina at Chapel Hill · USUniversity of Florida · US

Funding

Precision antiplatelet therapy after percutaneous coronary interventionR01HL149752 · NHLBI · UNIVERSITY OF FLORIDA · PI CAVALLARI, LARISA HUMMA, LEE, CRAIG R · 2020 to 2024
$3.5M
NHLBI NIH HHS R01 HL149752
6 · The paper itself

Abstract

Dual antiplatelet therapy with a P2Y

Indexed as

clopidogrelcytochrome P450 (CYP)pharmacogenomicsprecision medicinerace and ethnicity

Identifiers

PMID36082121
PMCPMC9445150
OpenAlexW4292832256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.