Evidence map›Paper›PMID 36082076›Full record

ArticleFrontiers in endocrinology2022

Increased plasma D-dimer levels may be a promising indicator for diabetic peripheral neuropathy in type 2 diabetes.

Lei Zhuang, Chao Yu, Feng Xu, Li-Hua Zhao, Xiao-Hua Wang, Chun-Hua Wang, Li-Yan Ning, Xiu-Lin Zhang, Dong-Mei Zhang, Xue-Qin Wang and 1 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  11. Associations Between Mean Platelet Volume and Various Factors in Type 2 Diabetes Patients: A Single-Center Study from Poland.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lei ZhuangDepartment of Endocrinology, Second People's Hospital of Nantong City, Nantong, China.
Chao YuDepartment of Clinical Laboratory, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Feng XuDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Li-Hua ZhaoDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Xiao-Hua WangDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Chun-Hua WangDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Li-Yan NingDepartment of Administration, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Xiu-Lin ZhangDepartment of Clinical Laboratory, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Dong-Mei ZhangMedical Research Center, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Xue-Qin WangDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.
Jian-Bin SuDepartment of Endocrinology, Affiliated Hospital 2 of Nantong University, and First People's Hospital of Nantong City, Nantong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Increased plasma D-dimer levels have been reported to be associated with a range of adverse health outcomes. This study aimed to determine whether plasma D-dimer is connected to diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes (T2D). Methods: This study was part of a series exploring the potential risks for DPN. All patients were questioned for neurologic symptoms, examined for neurologic signs, and received nerve conduction studies to collect nerve action potential onset latency, amplitude, and nerve conduction velocity (NCV). Composite Results: We finally recruited 393 eligible patients for this study, of whom 24.7% ( Conclusions: Increased plasma D-dimer levels may be a promising indicator for DPN in patients with T2D.

Indexed as

Diabetic NeuropathiesFibrin Fibrinogen Degradation ProductsDiabetes Mellitus, Type 2HumansPrognosisROC CurveFibrin Fibrinogen Degradation Productsfibrin fragment DD-dimerdiagnosisneuropathyrisktype 2 diabetes

Identifiers

PMID36082076
PMCPMC9445160

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.