Evidence map›Paper›PMID 36082064›Full record

Observational studyContrast media & molecular imaging2022

Diagnostic Accuracy of

Sarita Murtojärvi, Simona Malaspina, Ilpo Kinnunen, Terhi Tuokkola, Miikka-Juhani Honka, Virva Saunavaara, Tuula Tolvanen, Aleksi Schrey, Jukka Kemppainen

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sarita MurtojärviDepartment of Otorhinolaryngology, Turku University Hospital, Turku, Finland.ORCID 0000-0002-2420-9963
Simona MalaspinaTurku PET-Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0002-2701-8978
Ilpo KinnunenDepartment of Otorhinolaryngology, Turku University Hospital, Turku, Finland.ORCID 0000-0002-4576-2071
Terhi TuokkolaTurku PET-Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0003-3244-3116
Miikka-Juhani HonkaTurku PET-Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0001-9875-5863
Virva SaunavaaraTurku PET-Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0001-7858-5924
Tuula TolvanenTurku PET-Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0002-3308-1260
Aleksi SchreyDepartment of Otorhinolaryngology, Turku University Hospital, Turku, Finland.ORCID 0000-0002-5985-0259
Jukka KemppainenTurku PET-Centre, Turku University Hospital, Turku, Finland.ORCID 0000-0001-9390-1198
Turku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: In head and neck squamous cell carcinoma (HNSCC), the early diagnosis and efficient detection of recurrences and/or residual tumor after treatment play a very important role in patient's prognosis. Positron emission tomography (PET) using 2-deoxy-2- Methods: This retrospective observational cohort study consists of 104 patients from our center with histologically confirmed HNSCC. All patients received chemoradiotherapy (CRT) and underwent Results: PET/MRI was more sensitive (1.00 vs. 0.77) than PET/CT in the detection of locoregional recurrence. PET/MRI also had better negative (1.00 vs. 0.87) predictive values. AUCs for PET/MRI and PET/CT on patient-based analysis were 0.997 (95% CI 0.989-1.000) and 0.890 (95% CI 0.806-0.974), respectively. The comparison of sensitivity, AUCs, and negative predictive values revealed a statistically significant difference, Conclusion: Based on these results, PET/MRI might be considered the modality of choice in detecting locoregional recurrence in HNSCC patients, especially in the more advanced stages in the oral cavity, larynx, or nasopharynx.

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsChemoradiotherapyFluorodeoxyglucose F18HumansMagnetic Resonance ImagingNeoplasm Recurrence, LocalPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesSquamous Cell Carcinoma of Head and NeckFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID36082064
PMCPMC9433207
OpenAlexW4293199753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.