Evidence map›Paper›PMID 36082047›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2021

ICG-based dynamic contrast-enhanced fluorescence imaging guided open orthopaedic surgery: pilot patient study.

Shudong Jiang, Jonathan T Elliott, Jin Xing, Xu Cao, Xiaohan Yu, Xinyue Han, Rebecca E Dabrowski, Melanie L Christian, Eric R Henderson, Brian W Pogue and 1 more

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shudong JiangThayer school of Engineering, Dartmouth College, Hanover, NH.
Jonathan T ElliottDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Jin XingThayer school of Engineering, Dartmouth College, Hanover, NH.
Xu CaoThayer school of Engineering, Dartmouth College, Hanover, NH.
Xiaohan YuThayer school of Engineering, Dartmouth College, Hanover, NH.
Xinyue HanThayer school of Engineering, Dartmouth College, Hanover, NH.
Rebecca E DabrowskiDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Melanie L ChristianDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Eric R HendersonDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Brian W PogueThayer school of Engineering, Dartmouth College, Hanover, NH.
I Leah GitajnDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

Funding

Real-time Perfusion Imaging Guided Bone Debridement in Fracture Related Infection - A Precision Approach to DebridementR01AR077157 · NIAMS · DARTMOUTH-HITCHCOCK CLINIC · PI Ida L Gitajn · 2020 to 2026
$2.9M
Multimodal Fluorescence- and Imaging-Guided Surgical Navigation: Developing Methods for Subsurface, Indirect Visualization of Cancers Requiring Wide Local ExcisionK23EB026507 · NIBIB · DARTMOUTH-HITCHCOCK CLINIC · PI HENDERSON, ERIC R · 2018 to 2021
$679k
NIAMS NIH HHS R01 AR077157NIBIB NIH HHS K23 EB026507
6 · The paper itself

Abstract

Forty two patients with high energy open fractures were involved into the study to investigate whether an indocyanine green (ICG)-based dynamic contrast-enhanced fluorescence imaging (DCE-FI) can be used to objectively assess bone perfusion and guide surgical debridement. For each patient, fluorescence images were recorded after 0.1 mg/kg of ICG was administered intravenously. By utilizing a bone-specific kinetic model to the video sequences, the perfusion-related metrics were calculated. The results of this study shown that the quantitative ICG-based DEC-FI can accurately assess the human bone perfusion during the orthopedic surgery.

Indexed as

bone vascular perfusiondebridementdynamic contrast-enhanced fluorescence imagingindocyanine greenorthopaedic surgery

Identifiers

PMID36082047
PMCPMC9451047

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.