Evidence map›Paper›PMID 36082021›Full record

ArticleRevista panamericana de salud publica = Pan American journal of public health2022

[Efficacy of a standardized and simplified strategy for the treatment of high blood pressure in Chile: the HEARTS Initiative in the AmericasEficácia de uma estratégia padronizada e simplificada para o tratamento da hipertensão arterial no Chile: a iniciativa HEARTS nas Américas].

Luis Michea, Luis Toro, Natali Alban, Daisy Contreras, Patricia Morgado, Melanie Paccot, Maria Cristina Escobar, Eduardo Lorca

Open access · diamondAbstract readEnglish Abstract
In one paragraph

Article in Revista panamericana de salud publica = Pan American journal of public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Economic Evaluation of the HEARTS Standardized Hypertension Treatment Program With Fixed-Dose Combination Pills in Chile Primary Care Clinics.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Luis MicheaICBM Facultad de Medicina Universidad de Chile Santiago Chile ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Luis ToroCentro de Investigación Clínica Avanzada Hospital Clínico Universidad de Chile Santiago Chile Centro de Investigación Clínica Avanzada, Hospital Clínico Universidad de Chile, Santiago, Chile.
Natali AlbanServicio de Salud Metropolitano Suroriente Santiago Chile Servicio de Salud Metropolitano Suroriente, Santiago, Chile.
Daisy ContrerasServicio de Salud Metropolitano Suroriente Santiago Chile Servicio de Salud Metropolitano Suroriente, Santiago, Chile.
Patricia MorgadoSociedad Chilena de Hipertensión Santiago Chile Sociedad Chilena de Hipertensión, Santiago, Chile.
Melanie PaccotDivisión de Prevención y Control de Enfermedades Ministerio de Salud Santiago Chile División de Prevención y Control de Enfermedades, Ministerio de Salud, Santiago, Chile.
Maria Cristina EscobarOrganización Panamericana de la Salud Santiago Chile Organización Panamericana de la Salud, Santiago, Chile.
Eduardo LorcaHospital del Salvador Santiago Chile Hospital del Salvador, Santiago, Chile.
Hospital Clínico de la Universidad de Chile · CLHospital del Salvador · CLMinistry of Health · CLUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effectiveness of a standardized and simplified protocol based on the technical pillars of the HEARTS Initiative for the control of hypertensive patients in the Cardiovascular Health Program at the first level of care in Chile. Methods: Longitudinal observational study (historical cohort) in two family health centers at the first level of care in Santiago. The control of blood pressure in hypertensive adults using a standardized and simplified protocol was compared to the usual protocol based on national guidelines. Innovations in the standardized protocol included changes in how the health team is coordinated, initiation of pharmacological treatment immediately after confirmed diagnosis, standardized pharmacological treatment with a combination of at least two or three antihypertensive drugs taken daily in a single tablet. Follow-up was conducted after one year to assess the percentage of adherence to treatment and achievement of blood pressure control targets (< 140/90 mmHg). Results: A total of 1490 patients were evaluated: 562 who followed the standardized and simplified protocol, and 928 who were treated with the usual protocol (family health centers: 650; family health centers: 278). After one year, patients in the standardized and simplified protocol group had a higher proportion of adherence to blood pressure control targets (65% versus 37% and 41%, p<0.001) and higher adherence to treatment compared to those following the usual protocol (71% versus 18% and 23%, p<0.001). Conclusions: The results show that the standardized and simplified protocol is more effective than the usual protocol in controlling arterial hypertension in patients undergoing treatment at the first level of care in Chile. Its implementation at the national level could contribute to a decrease in major cardiovascular events.

Indexed as

Americasblood pressure monitoring, ambulatoryChileHypertensionquality of health care

Identifiers

PMID36082021
PMCPMC9446543
OpenAlexW4294734231

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.