Evidence map›Paper›PMID 36081948›Full record

ArticleFrontiers in pharmacology2022

Paeoniflorin alleviates liver injury in hypercholesterolemic rats through the ROCK/AMPK pathway.

Tong Liu, Ning Zhang, Lingya Kong, Sijie Chu, Ting Zhang, Guangdi Yan, Donglai Ma, Jun Dai, Zhihong Ma

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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  8. Network pharmacology-based study on the mechanism of Tangfukang formula against type 2 diabetes mellitus.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tong LiuSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Ning ZhangSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Lingya KongDepartment of Infectious Disease, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Sijie ChuSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Ting ZhangExperimental Center, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Guangdi YanSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Donglai MaSchool of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Jun DaiSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Zhihong MaSchool of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei, China.
Hebei University of Chinese Medicine · CNThird Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paeoniflorin (PF) is the main active component in

Indexed as

AMPKanti-inflammationanti-oxidationhypercholesterolemiapaeoniflorinrho kinase (ROCK)

Identifiers

PMID36081948
PMCPMC9445162
OpenAlexW4292834100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.